Senior Director, Head of Protein and Bioanalytical Solutions

ROLE SUMMARY

Pfizer is seeking a Senior Director to lead the Protein and Bioanalytical Sciences (PBS) Research team. This multidisciplinary team is at the forefront of creating protein reagents, antibodies, and antibody-drug conjugates (ADCs) for both preclinical discovery research and exploratory toxicology studies. The PBS team responsibilities includes the biophysical characterization of biologics, drug formulation, stability testing of new therapeutic compositions, and the bioanalytical assessment of ADC payload release and cellular deposition.

The appointed leader will drive a dynamic and collaborative team, focusing on expanding technological capabilities to enhance the capacity and efficiency of key material delivery, crucial for advancing the discovery of novel ADCs aimed at cancer treatment. As a strategic and operational cornerstone, the PBS team leader will collaborate with other senior members of the ADC Discovery Research Group to build and drive Pfizer's ADC strategy and advance Pfizer's preclinical pipeline.

KEY RESPONSIBILITIES

• Lead a team of 30+ scientists including PhD level
• Accountable for appropriate resourcing and timely delivery of requested materials and data to enable efficient workflows
• Create and manage prioritization efforts of sub-teams within the PBS group to ensure optimal portfolio progression and scientific rigor
• Develop the strategy for PBS to improve capacity and efficiency of platform technologies through innovation and application of new technologies, including automation, external capabilities and collaborations
• Leverage new technologies and existing bioanalytical approaches to characterize protein biologics and ADC mechanisms of action
• Work closely with Research and external departments to balance priorities between clinical-stage programs and pre-IND programs, with seamless transfer of knowledge and processes from research to the Pharmaceutical Sciences team
• Provide supervision and mentorship of individuals in team, establishing the technical vision, implementation of new technologies and enabling personal growth of team members
• Promote a culture of professionalism and collaboration focused on patient outcomes in alignment with company goals and values

BASIC QUALIFICATIONS

• Ph.D. in Biochemistry, Chemistry or related discipline
• Minimum 15 years post Ph.D. related oncology or chemistry experience in industry, including technical and scientific experience in drug discovery and preclinical development 
• Expertise in ADC synthesis, including protein generation, small molecule synthesis, biochemical conjugation and in vitro and in vivo molecule stability characterization
• Deep experience building, leading and directly managing large teams, capable of giving feedback, coach, mentor, and develop employees 
• Demonstrated track record in collaborative research in ADC Oncology drug discovery programs with strong business acumen and communication skills
• Ability to collaborate across teams and a variety of disciplines to create and communicate scientific strategy and priorities

PREFERRED QUALIFICATIONS

• Prior experience of scaling and process improvement in a high-throughput production environment, experience in lean six sigma a plus 
• Strong track record of scientific accomplishments in industry as evidenced by publications or other equivalent achievements
• Experience getting results through creativity and unique problem solving
• A leader who uses data driven science and metrics to reinforce decision making

The annual base salary for this position ranges from $205,400.00 to $342,400.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 25.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.