Jobs and Careers
KA
AD / Director Program Management
Karyopharm TherapeuticsRemote, United States, United StatesRemotefull_timeVerifiedPosted 29 Oct 2025
💰 $275,000/yr($205,000/yr – $275,000/yr)
About the role
Role Overview & Key Functions:
As a Karyopharmer, reporting to the Senior Director Program Management, you will positively impact patients’ when you:
- Acts as the COO of Program, partnering with the Program Lead to drive team alignment on program strategy and operationalize the strategic vision
- Provides an independent voice to shape the program strategy and acts as an integrator of cross-functional input to drive optimal decisions for the program
- Leads effective Program Team meetings and presents program strategy to various audiences
- Accountable for the cross-functional execution of one or more program strategy plans. Can be assigned to any disease area, at any stage of development
- Manages program timeline, cost, quality, and risk mitigation as well as timely escalation where needed
- Acts as a leader in the PM organization to help build cross-portfolio capabilities. Recognizes consistent challenges and innovates solutions, shares best practices and coaches more junior PMs
Candidate Profile & Requirements:
- Manages the effective operations of Karyopharm’s cross-functional program teams, focused on the development of one or more disease area programs
- Partners with the Program Lead to drive development of the Program Strategy Plan, adding value by deriving insights from cross-functional discussions and summarizing those insights in a plan that can be easily communicated and implemented across the enterprise
- Partners with the Program Lead to coordinate the development, and implementation of high quality, global, cross-functional, integrated project plans that are aligned with the program strategy
- Fosters a high-performing team by championing team norms, operating principles and introducing best practices. Monitors the heath and operating efficiency of the team on a regular basis and shares feedback
- Mentors and coaches team members to drive accountability, alignment, and excellence
- Facilitates effective business decisions by ensuring integration of key cross-functional input and robust analysis of scenarios. Ensures all decisions are assessed as to their impacts and communicated to stakeholders in a transparent and timely manner
- Highlights key interdependencies and downstream impacts of strategic decisions to stakeholders
- For programs that are being jointly developed, works closely with alliance management and partner counterparts to ensure appropriate level of engagement in program strategy discussions
- Responsible for maintaining and updating program dashboards for assigned program team(s), provides regular status reports on key deliverables, risks and issues to Program Lead
- Proactively coordinates risk management and ensures contingency and/or risk mitigation plans are developed
- Works with functions to procure adequate resources to achieve project objectives in planned timeframes
- Acts as a change agent and leads process improvement initiatives for continuous improvement and as it relates to improving project delivery
- May delegate project level tasks/follow-up and provides oversight to Project Manager(s) with potential for direct reporting responsibility
- Works creatively and analytically in a problem-solving environment demonstrating teamwork, innovation, and excellence
QUALIFICATIONS:
- Bachelors degree in a science related or business related field required. Advanced degree preferred (e.g., MBA, MS, PhD, PharmD).
- Five (5) or more years of demonstrated drug development project/program management experience with 7+ years of relevant experience in the Pharmaceutical or related Life Sciences industry.
- Strong knowledge in drug discovery and development and/ or clinical research or related health sciences field with solid understanding of project strategy, interdependencies, and disease content to contribute to strategic discussions
- Experience with operational study start-up into Registrational/Phase 3 trials with a deep understanding of the necessary steps required for market application submissions in multiple regions (US, EU, Japan, China)
- Well-developed program leadership and strategic thinking skills, experience in development of Program Strategy Plans
- Experience in partnering with functional leads across the organization to meet strategic goals and demonstrated ability to collaborate in a cross-functional environment
- Excellent organizational skills ability to manage several priorities simultaneously
- Ability to influence without authority and to act as a leader on a wide range of complex activities where judgment and expertise are critical to project success
- Strong communicator able to integrate information and tailor messages to aud
Apply for this role
Generate a tailored application kit with a matched cover letter, interview prep, and CV highlights — in under 60 seconds.
Apply Now →Generate Application KitFree account required — sign up in 30s