Senior Research Associate, Exploratory Biology

The Company:   

WHAT IF THE SECRET OF HEALTH LIES AT THE CENTER OF DISEASE? At Sonata Therapeutics, we are designing Network Medicines(TM) that reprogram diseased cells to become the coordinators of cure.  

Through a combination of our proprietary genetic library, comprehensive biochemical and functional characterization, and the latest advancements in machine learning algorithms, we are generating a deep understanding of how to reshape multicellular networks to guide the development of transformative therapeutics. While initially focused on oncology, our network-based approach is applicable across many intractable diseases.  

Sonata Therapeutics was founded by Flagship Pioneering, an organization dedicated to the origination and development of first-in-category life sciences companies.  Since 2000, Flagship has originated and fostered the development of nearly 100 scientific ventures resulting in $20+ billion in aggregate value, 500+ issued patents, and more than 50 clinical trials for novel therapeutic agents.   

 

The Position  

Due to our growth, we are on the hunt for a Senior Research Associate, Exploratory Biology who will participate in exploring the mechanisms of disease biology and develop new Network MedicinesTM that will bring hope to patients with unmet medical needs. . 
 
You will support the team in building robust translational packages focused on identifying relevant indications, evaluating target engagement and immune responses, as well as establishing pharmacodynamic and predictive biomarkers for Sonata’s lead drug candidates. You will be responsible for the development and execution of in vitro assays interrogating proof-of-concept and underlying biological mechanism of action for our therapeutics. We are searching for enthusiastic, innovative, and highly motivated individuals who are comfortable working in a fast-paced entrepreneurial environment.  

Sonata Therapeutics offers the challenge and opportunity to work at an early stage, big concept biotechnology company. Your efforts will have a lasting impact on our development programs leading to future success in the clinic.    

 

You will be making a significant impact by... 

• Contributing to the design of experimental plans for translational studies. 
• Executing experiments, interpreting, and validating results, and communicating data to scientific team. 
• Actively collaborating with others to achieve company objectives. 

 

As an excellent candidate, you will possess… 

• Bachelor’s or master’s degree and at least 3 years of relevant research experience is required, preferably focused disease biology. 
• Expertise in mammalian cell culture techniques (3D culture experience desirable). 
• Experience with cellular assays and standard molecular biology methods (Western blot, qPCR). 
• Experience with IHC or basic histology is preferred  
• Experience with HTS assay, tissue handling and testing therapeutics is preferred. 
• A demonstrated ability to work independently as well as collaboratively with highly skilled teams.  
• The drive and time-management skills to efficiently support multiple projects in parallel while operating on ambitious timelines.  
• Excellent communication and presentation skills to convey complex technical information in a clear and concise manner. 
• The motivation to thrive in an entrepreneurial environment by being team-oriented, focused on execution, and responsive to company goals. 

   

 

Sonata Therapeutics and Flagship Pioneering are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, or veteran status.