Principal Bioinformatics/Software Test Engineer

Help us change lives

At Exact Sciences, we’re helping change how the world prevents, detects and guides treatment for cancer. We give patients and clinicians the clarity needed to make confident decisions when they matter most. Join our team to find a purpose-driven career, an inclusive culture, and robust benefits to support your life while you’re working to help others.

Position Overview

At Exact Sciences, we are cancer fighters. We are united by our mission to change lives by providing earlier, smarter answers. Through advances in cancer detection and treatment guidance, we will help eradicate the disease and the suffering it causes.

We are seeking a highly experienced Principal Software Test/Quality Engineer to lead the design, implementation, and execution of software testing strategies for medical diagnostic platforms focused on cancer screening and early detection. This role is a key contributor to ensuring that our software meets the highest standards of safety, effectiveness, and compliance with regulatory requirements.

You will collaborate closely with software developers, bioinformatics scientists, systems engineers, and quality/regulatory teams to build robust test frameworks, identify risks, and ensure reliable product performance that directly impacts patient outcomes.

Essential Duties

Include, but are not limited to, the following:

• Define and implement testing strategies that encompass bioinformatics pipelines, LIMS workflows, and other Clinical Laboratory Software.
• Serve as a technical mentor to the test engineering team, providing guidance in SDLC, Agile, test automation, risk-based testing, and defect prevention strategies.
• Participate in project design reviews to ensure that application designs adhere to Quality Engineering guidelines and standards.
• Apply general and QE technical expertise (e.g., system stack, test automation frameworks) and knowledge of QE standards and best practices (e.g., risk assessment methodology,) to develop quality plans that deliver solutions to the business in the most efficient and effective manner.
• Set clear objectives for team members of full-time and on-shore/off-shore contractors utilizing best practice models and metrics to continually assess progress and improve.
• Directly influence and co-define Quality Engineering strategic direction, roadmap, technology, and processes. Partner with business and technology teams to prioritize roadmaps, requirements, balancing business need with capacity and technology constraints.
• Deliver software products that meet ISO13485, FDA compliant standards along with supporting documentation.
• Provide technical leadership and guidance to the internal cross-functional project team to ensure that project execution is consistent with the quality plan and SDLC.
• Works closely with internal cross-functional and external teams to influence the complete system architecture and design for systems associated with existing domains and or conceptual like-for-like technology upgrades/migrations/replacements to ensure fully testable, functioning, reliable and performing integrated systems.
• Create adaptive and Innovative Quality Engineering architecture, tools, and techniques, which includes optimization of hybrid off-shore/on-shore resourcing and application of best of breed, risk-based testing methods, levels, and types.
• Consistent demonstration of exceptional leadership qualities, including but not limited to the ability to attract and retain the best team, foster a culture of high performance, lead with integrity, humility, accountability, and courage, and set a clear vision to energize teams towards the future.   
• Effectively manage, support, and guide your team, including, but not limited to delegating tasks and responsibilities, assess employee performance and provide helpful feedback and training opportunities.
• Uphold company mission and values through accountability, innovation, integrity, quality, and teamwork.
• Support and comply with the company’s Quality Management System policies and procedures.
• Maintain regular and reliable attendance.
• Ability and means to travel between local Exact Sciences locations.
• Ability to act with an inclusion mindset and model these behaviors for the organization.

Minimum Qualifications

• Bachelor’s Degree in Engineering, Science, Biology, Chemistry, or related field as outlined in the essential duties; or High School Diploma/General Education Degree and 10 years of relevant experience as outlined in the essential duties in lieu of Bachelor’s Degree.
• 10+ years of experience in Engineering or Infor