Senior Bioinformatics Scientist, BioPharma Collaborations

Company Description

Guardant Health is a leading precision oncology company focused on helping conquer cancer globally through use of its proprietary blood tests, vast data sets and advanced analytics. The Guardant Health Oncology Platform leverages capabilities to drive commercial adoption, improve patient clinical outcomes and lower healthcare costs across all stages of the cancer care continuum. Guardant Health has launched liquid biopsy-based Guardant360®, Guardant360 CDx and GuardantOMNI® tests for advanced stage cancer patients. These tests fuel development of its LUNAR program, which aims to address the needs of early stage cancer patients with neoadjuvant and adjuvant treatment selection, cancer survivors with surveillance, asymptomatic individuals eligible for cancer screening and individuals at a higher risk for developing cancer with early detection. 

Job Description

The Bioinformatics, BioPharma team at Guardant Health is focused on partnerships with leading biotech and pharma companies who are at the forefront of cancer therapeutics and diagnostics. In this role, you will help lead the bioinformatics and data analysis in support of the late-stage oncology products and other emerging technologies. You will work with a number of BioPharma and clinical customers, tailor personalized analyses for each organization, and tackle some of the most interesting biological and technical questions related to cancer diagnostics and therapy selection.

You will contribute to BioPharma project initiatives in-house, including development of novel bioinformatic and analytical methods. As a part of the Bioinformatics and BioPharma teams, you will have the opportunity to innovate and implement your ideas to continuously improve our oncology products and analytics to adapt to the changing landscape of BioPharma needs.

You will work closely with multiple teams across Guardant Health, including Bioinformatics, Medical Affairs, Software, Business Development, Technology Development, and Operations. You will gain first-hand experience working with experts in each of these areas to accomplish projects related to Guardant Health’s BioPharma business. You will work together with our collaborators in industry, hospitals and academia on high-impact translational research and publish on your findings. You will have access to the unprecedented compendium of data collected at Guardant Health and you will be able to (and should be excited to!) leverage this data for tumor biology and technological insights.

Qualifications

• PhD in bioinformatics, genomics or related fields
• 3+ years relevant experience in Pharmaceutical or Biotech industry
• Extensive knowledge of molecular biology and cancer genomics
• Expertise in scripting language – R and/or Python and linux shell environment (Bonus: experience developing novel / custom algorithms for interpretation of NGS data)
• Excellent data analysis skills and working knowledge of statistical methods
• Experience with NGS data and landscape of bioinformatics tools (Bonus: direct experience with epigenomic data)
• Desire and ability to dig deeply through various data types to seek out answers
• Great communication and presentation skills, ability to present clearly and effectively to stakeholders across organizations
• Ability to work well in a fast-paced startup environment, delivering high-quality results under tight timelines
• Ability to synthesize high-level concepts, drive projects forward, while maintaining attention to detail
• Strong team player: ability to work together with your team as well as cross-functionally and even across institutions, to accomplish your goals

Additional Information

Hybrid Work Model: At Guardant Health, we have defined days for in-person/onsite collaboration and work-from-home days for individual-focused time. All U.S. employees who live within 50 miles of a Guardant facility will be required to be onsite on Mondays, Tuesdays, and Thursdays. We have found aligning our scheduled in-office days allows our teams to do the best work and creates the focused thinking time our innovative work requires. At Guardant, our work model has created flexibility for better work-life balance while keeping teams connected to advance our science for our patients.

Covid Vaccination Policy:  Starting January 7, 2022, Guardant Health will require all employees to be fully vaccinated to either (a) establish that they have been fully vaccinated against COVID-19; or (b) request and obtain an approved exemption from Guardant’s COVID-19 U.S. Vaccination Policy as a reasonable accommodation, as consistent with applicable laws.  An employee is considered fully vaccinated against COVID-19 two weeks after receiving the second dose of a two-dose vaccine or