Senior Associate Scientist, In Vivo Pharmacology

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

When you join BMS, you are joining a diverse, high-achieving team united by a common mission. 

The Neuroscience TRC is committed to the development of transformational therapeutics for patients with neurodegenerative, neuromuscular and neuropsychiatric diseases. A network of internal and external partnerships across neurodegenerative and neuropsychiatric diseases and treatment modalities (small molecules, biologics and genetic medicines) supports our ambition to become leaders in neuroscience. Internal research focuses on causal human biology, matching therapeutic modality to molecular mechanism, and translational discovery enabling a rapid path to clinical proof-of-concept. 

Areas of interest include, but are not limited to, the identification of disease modifying and symptomatic therapies for neurodegenerative, neuro-inflammatory neuropsychiatric and neuromuscular diseases; approaches to modulate protein clearance and reduce or eliminate toxic protein production; emerging technologies (RNA, DNA targeting) that when matched to underlying causal human biology may deliver a precision medicine portfolio with a high probability of translational success; AI/ML in target identification drug discovery; neuroimaging and fluid biomarkers to track disease progression and target engagement; novel blood brain-barrier technologies to enhance delivery of biotherapeutics and genetic medicines across the blood-brain barrier.

Here, you’ll get the chance to grow and thrive through uncommon opportunities and scope. You’ll pursue innovative ideas while advancing professionally alongside some of the brightest minds in biopharma.

Position Summary:

The Neuroscience Thematic Research Center (Neuro TRC) leverages external collaborations and internal research to establish a diverse portfolio targeting unmet needs in neurodegenerative, neuropsychiatric, neuroinflammatory and neuromuscular, diseases.   The Senior Associate Scientist, Neuroscience Discovery, in collaboration with other members of the Neuroscience TRC, implements in vivo studies that enable rapid progression of drug candidates from target identification through clinical proof-of-concept. This laboratory-based role is based in Cambridge, MA, and will join a team of scientists responsible for supporting our collaborative drug discovery mission.

Position Responsibilities:

In the role as a Senior Associate Scientist, In Vivo Pharmacology, the ideal candidate will:

• Implement studies designed to evaluate novel BBB delivery technologies and therapeutic modalities applied to diseases of strategic interest to the Neuroscience TRC

• Maintain and integrate transgenic and other animal models to evaluate and select drug candidates for further investment

• Support programs employing novel delivery technologies for neurodegenerative and neuromuscular disorders

Basic Qualifications:

• Bachelor’s Degree

  • 4+ years of academic and / or industry experience

Or

• Master’s Degree

  • 2+ years of academic and / or industry experience

Preferred Qualifications:

• BA, BS or MS with 4+ years of experience in drug discovery research spanning small molecule, biotherapeutics and genetic medicines discovery, with an emphasis on the evaluation of novel delivery technologies and approaches to enhance CNS delivery of therapeutic agents, using genetically modified animals where appropriate

• Hands on experience in in vivo pharmacology, including small animal handling, surgical techniques, maintenance and breeding of transgenic animal colonies, coordination of research