Scientist – RNA Sequencing / ddPCR

Work Schedule

First Shift (Days)

Environmental Conditions

Adherence to all Good Manufacturing Practices (GMP) Safety Standards, Laboratory Setting

Job Description

Scientist – RNA Sequencing / ddPCR

Position:

Shift: Full-Time; Monday – Friday; 8am-5pm EST

ONSITE:

This is a fully onsite role based at our customer’s site in (insert location – i.e. Boston, MA). We welcome applicants from all locations within the US. Please note that relocation assistance is not provided for this position, and any relocation costs will be the responsibility of the candidate.  

Must be legally authorized to work in the United States without sponsorship. 

Must be able to pass a comprehensive background check, which includes a drug screening. 

At Thermo Fisher Scientific, you’ll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life - enabling our customers to make the world healthier, cleaner and safer. We provide our teams with the resources needed to achieve individual career goals while taking science a step beyond through research, development and delivery of life-changing therapies. With clinical trials conducted in 100+ countries and ongoing development of novel frameworks for clinical research through our PPD clinical research portfolio, our work spans laboratory, digital and decentralized clinical trial services. Your determination to deliver quality and accuracy will improve health outcomes that people and communities depend on – now and in the future.

Thermo Fisher's clinical research business is a leading global contract research organization and world leader in serving science. We are passionate, deliberate, and driven by our mission – to enable our customers to make the world healthier, safer, and cleaner.

Our Laboratories Functional Service Partnership (FSP) team plays a direct role in advancing drug development by creating sustained groups of talent within our customers’ organizations to provide long-term support. Through this collaborative approach, our professionals bring their commitment to excellence, industry knowledge, and operational strength directly into customer environments, helping to enhance capabilities and advance the delivery of life-changing therapies.

Key responsibilities:

• Independently design, execute, troubleshoot, optimize, and interpret analytical method development experiments using digital PCR, qPCR, ddPCR, bulk RNA sequencing
• NanoString nCounter, Oxford Nanopore sequencing NICE TO HAVE
• Perform DNA/RNA extraction, sequencing library preparation, sequencer operation, digital PCR workflows, and other associated laboratory procedures with a high standard of technical rigor.
• Design and conduct experiments to evaluate assay performance characteristics, including accuracy, precision, linearity, sensitivity, and technology comparisons.
• Analyze and interpret data using R, GraphPad Prism, JMP, and related bioinformatics tools to support assay development, process characterization, and technology evaluation.
• Organize, analyze, and summarize data for project updates, technical reports, study summaries, and internal presentations.
• Author and review protocols, SOPs, technical reports, study documentation, and regulatory support documents.
• Collaborate cross-functionally with partners in analytical development, process development, research, and other teams to support analytical strategy and project goals.
• Operate, maintain, and troubleshoot laboratory instrumentation, including NextSeq 2000, NovaSeq X, PromethION 24, NanoString nCounter Prep Station/Digital Analyzer, and digital PCR platforms.
• Maintain laboratory organization, instrument readiness, reagent inventory, and compliance with documentation and laboratory best practices.

Education and Experience:

• Bachelor's degree in lab sciences such as Chemistry, Biochemistry, Material Science, Immunology, Biology, Molecular Biology or similar
• Scientist: Previous experience that provides the knowledge, skills, and abilities to perform the job (comparable to 2+ years’)
• OR Masters degree

In some cases, an equivalency, consisting of a combination of appropriate education, training and/or directly related experience, will be considered sufficient for an individual to meet the requirements of the role.

Knowledge, Skills and Abilities:

• Digital PCR (ddPCR, dPCR)
• qPCR
• NanoString nCounter (NICE TO HAVE)
• Bulk RNA-sequencing library preparation and sequencing
• DNA/RNA extraction
• Oxford Nanopore library preparation and sequencing workflows
• Statistical