Post-Doctoral Fellow

Job Details

Acquire proficiency in 3D electron microscopy (EM) specimen handling and preparation for data acquisition as well as in setting up the data acquisition using transmission electron microscope (TEM, tilt-angle series) and focused ion beam scanning electron microscope (FIB-SEM, slice-and-view workflow). Understand the sample behavior during acquisition and understand the sources of acquisition errors/noises that affect the post-acquisition 3D reconstruction and analysis.

Job Description

Implement and develop software codes used for post-acquisition image stack optimization, distortion corrections and stack alignment. Implement and develop AI/machine learning workflows for 3D reconstructions, automated image segmentations, 3D ultrastructural and geometric analyses from the aligned tomograms. Coordination and supervision of the use of computers of the FIB-SEM lab dedicated to 3D image analysis.

Contribute to 3D-EM projects focusing on the morphometric/geometric analysis of mitochondrial networks, membrane formations and organelle encounters in the brain and other excitable tissues as well as in some select non-excitable tissues for reference. Communicate the methodological advances at conferences and peer-reviewed scientific publication platforms. Manage data sharing and code availability.
The candidate:

Work Shift

Workday Day (United States of America)

Worker Sub Type

Regular

Employee Entity

Thomas Jefferson University

Primary Location Address

1020 Locust Street, Philadelphia, Pennsylvania, United States of America

Nationally ranked, Jefferson, which is principally located in the greater Philadelphia region, Lehigh Valley and Northeastern Pennsylvania and southern New Jersey, is reimagining health care and higher education to create unparalleled value. Jefferson is more than 65,000 people strong, dedicated to providing the highest-quality, compassionate clinical care for patients; making our communities healthier and stronger; preparing tomorrow's professional leaders for 21st-century careers; and creating new knowledge through basic/programmatic, clinical and applied research. Thomas Jefferson University, home of Sidney Kimmel Medical College, Jefferson College of Nursing, and the Kanbar College of Design, Engineering and Commerce, dates back to 1824 and today comprises 10 colleges and three schools offering 200+ undergraduate and graduate programs to more than 8,300 students. Jefferson Health, nationally ranked as one of the top 15 not-for-profit health car