Precision Medicine Technology Portfolio Sr. Manager

Career Category

Job Description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Precision Medicine Technology Portfolio Sr. Manager

What you will do

Let’s do this. Let’s change the world. In this vital role you will provide strategic leadership and operational oversight for a portfolio of technology capabilities that enable Amgen’s Precision Medicine strategy. This role will partner deeply with Translational Sciences, Biospecimen Management, Clinical Operations, and multiple Technology teams to define future-state needs, shape the technology roadmap, and guide delivery of high-value solutions.

• Lead the coordination and ongoing refinement of the Precision Medicine technology portfolio - orchestrating alignment between business needs and technology capacity, including investment prioritization, resource planning, and performance measurement.
• Establish and manage PMed portfolio governance routines that enable clear decision-making and alignment across scientific and technology partners.
• Maintain a multi-year technology roadmap that reflects scientific strategy, operational needs, and emerging external trends.
• Translate scientific and translational use cases into actionable technology requirements, in partnership with Technology Business Analysts.
• Partner with scientific and operational groups to understand problems, find opportunities, and ensure business needs are articulated to enable technology solutions supporting end-to-end biospecimen, biomarker, and data workflows.
• Collaborate with technology architects and product teams to evaluate solutions, ensure interoperability, and support long-range architecture planning.
• Facilitate project intake, scoping, and prioritization in alignment with strategic objectives.
• Support delivery teams through requirements clarification, risk identification, and cross-functional alignment.
• Project management for high-value, business critical projects.
• Develop and maintain portfolio-level KPIs and reporting to track value, health, and delivery progress.
• Develop and maintain RACI to ensure effective partnerships across critical multi-functional activities.
• Drive communication and change management strategies to ensure adoption of new capabilities across scientific teams.
• Partner with stakeholders to assess readiness, support training, and ensure technologies integrate seamlessly into scientific workflows.
• Serve as a strategic connector across Precision Medicine, Translational Sciences, Clinical Operations, CfDA, Enterprise and R&D Technology, Data and Analytics, and Governance functions.
• Prepare and deliver concise, decision-ready materials for senior leadership engagement.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a leader with these qualifications:

Basic Qualifications:

Doctorate degree and 2 years of relevant experience

OR

Master’s degree and 4 years of relevant experience

OR

Bachelor’s degree and 6 years of relevant experience

OR

Associate’s degree and 10 years of relevant experience

OR

High school diploma / GED and 12 years of relevant experience

Preferred Qualifications:

• Experience working at the interface of science and technology within a biopharma or life sciences environment.
• Proven ability to lead portfolio management, strategic planning, or enterprise technology governance.
• Working knowledge of translational science, biospecimen lifecycle management, biomarker technologies, or related R&D domains.
• Understanding of data architectures, digital lab technologies, and informatics platforms supporting translational and clinical workflows.
• Strong critical thinking, systems thinking, and problem-solving capa