Vice President, Oncology Lifecycle Leader (GI)

Position Summary: Natera is a global leader in cell-free DNA testing focused on changing the management of disease in reproductive health, oncology, and organ transplantation. Signatera is a personalized, tumor-informed test for molecular residual disease (MRD) assessment and surveillance monitoring in patients previously diagnosed with cancer.  Signatera is covered by Medicare for colorectal cancer, muscle invasive bladder cancer, high-risk breast cancer, ovarian cancer, lung cancer, and immunotherapy response monitoring for any solid tumor. 

As the Vice President, Oncology Lifecycle Leader (GI), you will lead a team of Lifecycle Leaders in shaping the vision and strategy for Natera’s oncology product portfolio in GI cancers. Your leadership will drive a cohesive, cross-functional approach—partnering with medical, sales, business development, and other key teams—to position our products effectively and address critical unmet needs in cancer care.

Reporting directly to the VP of Oncology Lifecycle Management, you will own the GI disease area strategy, and make high-impact decisions to maximize the clinical and commercial success of our oncology solutions.  

Primary Responsibilities: 

• Own the lifecycle planning and success of GI cancers, collaborating with cross-functional teams to develop and execute a strategic plan that drives usage, awareness, and advocacy across key stakeholders worldwide.

• Expand Signatera access across GI tumors – prioritize key indications, own evidence roadmaps, close evidence gaps and submit for coverage

• Lead and inspire teams – Manage a team of 2-3 GI specific Lifecycle Leaders, operating with a culture of accountability and collaboration

• Establish tumor-specific goals to be owned by the lifecycle team and across functions.

• Serve as a critical member on clinical / medical teams, helping define and prioritize key indications while identifying and addressing evidence gaps.

• Monitor performance & mitigate risks – In close partnership with Marketing team, track performance and deliver against GI commercial and medical goals, identifying potential issues / risks and implement mitigation strategies

• Serve as a critical member on commercial subteams, helping to maximize Natera potential by escalating and addressing critical barriers that limit commercial adoption.

• Maintain a deep expertise in the GI cancers space by integrating real-time customer insights, publications, data presentations, competitive and market intelligence.

• Shape the value proposition for Natera’s oncology products in collaboration with Medical Affairs and Commercial Marketing, leveraging clinical evidence and market dynamics.

• Regularly present strategic plans and progress to executive leadership.

Qualifications: 

• Bachelor’s degree, Advanced degree preferred (MBA or PhD)

• GI oncology market experience strongly preferred

• 10-15 years experience in product marketing, market analytics at a pharmaceutical / biotech company

• Previous KOL management experience preferred

• Working knowledge of oncology molecular testing / biomarkers

• ~25% travel required (advisory boards, congresses, sales / marketing meetings, customer meetings)

Knowledge, Skills, and Abilities: 

• Ability to lead without authority, influence and inspire individuals

• Proven strategic agility with an enterprise mindset and ability to operate with executive presence

• Ability to partner and collaborate across a broad range of internal and external partners 

• Strong customer orientation and focus, particularly establishing thought leader relationships

• Proven ability to communicate the complex simply (biomarkers, multiple indications, etc.)

• Strong organizational / time management skills; manage and complete multiple projects

The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.Remote USA$220,500—$335,400 USD

OUR OPPORTUNITY

Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earl