Clinical Program Manager

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers.  The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity:

This is a unique opportunity for a Clinical Program Manager (CPM). You will be responsible for driving operational strategy across multiple trials within entire clinical programs or multiple trials across indications, and support program-level governance, timelines, and decision-making.  This position will report into the Associate Director, Clinical Operations.

Responsibilities:

• Provide expert thought leadership at the discipline level on highly complex and business critical assignments and begins to develop new ideas.

• Lead the Clinical Study Execution Team (CSET) meetings and ensure trial timelines are met.

• Develop trial execution strategy and timelines across study(ies).

• Participate in multiple department or interdepartmental strategic initiatives under limited supervision as it relates to study-specific initiatives.

• May serve as a resource for others with regard to a specific study trial.

• Maintain audit/inspection readiness and oversee TMF compliance.

• Collaborate with cross functional partners in drafting study documents such as protocols, ICFs, CRFs, monitoring plans, etc.

• Drive consistency in processes and tools across studies.

• Contribute to development of RFPs and participates in selection of CROs/vendors.

• May be asked to train CROs, vendors, investigators, and study coordinators, as well as cross-functional partners on study requirements.

• Oversee CROs, vendors, and key external partners to ensure study delivery.

• Make recommendations to the development of study-level budget.

• Participate in the recruiting and hiring process.

• Mentor and train Clinical Trial Managers (CTMs), Clinical Trial Management Associates (CTMAs), and Clinical Trial Assistants (CTAs).

• Conduct risk management, contingency, and scenario planning.

• Participate in other Clinical Operations activities as appropriate.

Required Skills, Experience and Education:

• BS, BA, or RN in a relevant scientific discipline.

• 8+ years of relevant experience in the pharmaceutical or biotech industry, preferably in Clinical Operations or Clinical Research related experience.

• Expert knowledge of FDA and EMA Regulations, ICH Guidelines, GCP, and familiarity with standard clinical operating procedures.

• High-level cross-functional collaboration; strategic thinking across trials and functions.

• Strategic thinking across clinical trials and functions with strong program-level planning and risk management.

• Independently apply clinical trials knowledge to problems that arise during the conduct of a study.

• High sense of priority and commitment to excellence in the successful execution of deliverables.

• Ability to analyze operational data, contribute with a mind on quality, timeliness and fiscal responsibility, make and drive decisions, multi-task, prioritize tasks, anticipate challenges, and execute on goals as a member of an interdisciplinary team.

• Travel may be required (~25%).

Preferred Skills:

• Decision-making skills.

• Has familiarity working with vendor systems/portals (e.g., eTMF, EDC, IRT, CTMS).

• Oncology experience, early and/or late stage, strongly preferred. #LI-Hybrid #LI-JC1

The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.

Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes