Sr. Clinical Research Coordinator, Clinical Operations

<div class="content-intro"><p><strong>Company Overview:</strong></p> <p>Prime Medicine is a leading biotechnology company dedicated to creating and delivering the next generation of gene editing therapies to patients. The Company is leveraging its proprietary Prime Editing platform, a versatile, precise and efficient gene editing technology, to develop a new class of differentiated, one-time, potentially curative genetic therapies. Designed to make only the right edit at the right position within a gene while minimizing unwanted DNA modifications, Prime Editors have the potential to repair almost all types of genetic mutations and work in many different tissues, organs and cell types.  </p> <p>Prime Medicine is currently progressing a diversified portfolio of investigational therapeutic programs organized around our core areas of focus: hematology, immunology & oncology, liver and lung. Across each core area, Prime Medicine is focused initially on a set of high value programs, each targeting a disease with well-understood biology and a clearly defined clinical development and regulatory path, and each expected to provide the foundation for expansion into additional opportunities. For more information, please visit <a href="http://www.primemedicine.com/">www.primemedicine.com</a>.</p></div><p> </p> <p>Position Overview:</p> <p>Join a collaborative, agile and dynamic Clinical Development Operations (CDO) team by leading and contributing to transformative clinical programs for patients in rare diseases and beyond.</p> <p>In this position, you will be hands-on in day-to-day study execution, working closely with internal study team members, clinical sites, and external CROs and vendors. This position is ideal for someone who thrives in a fast-paced, evolving environment, is comfortable wearing multiple hats, and is eager to learn more about clinical trial management and execution. This is a hybrid role requiring a combination of in-office presence (Watertown, MA) and remote work, with expectations aligned to team and business needs.</p> <p> </p> <p>Key Responsibilities:</p> <p>· Support the execution of clinical trials from startup through closeout, ensuring adherence to protocol, timelines, and quality standards</p> <p>· Assist with site startup activities, including regulatory document collection, IRB/EC submissions, and site readiness/activation</p> <p>· Support development of study and site-facing materials (e.g., ICFs, recruitment materials, study manuals, CCGs, study tools) and coordinate cross-functional review and approval</p> <p>· Prepare and maintain meeting minutes, action items, and follow-ups for key study team meetings</p> <p>· Maintain study documentation (e.g., sponsor TMF oversight and