Postdoctoral Research Associate, Cellular and Molecular Medicine (Full-Time)
University of ArizonaAbout the role
We are seeking a highly motivated individual to join the Sadayappan Laboratory within the Department of Cellular and Molecular Medicine at the University of Arizona. The environment features a world-class group of investigators with vast expertise in cardiovascular and skeletal muscle science. The laboratory is focused broadly on studying the regulation of sarcomeric proteins such as cardiac myosin heavy chain, including its S2 subfragment, and cardiac myosin binding protein-C (cMyBP-C), protein-protein interactions, myopeptide-based therapeutics, gene therapies, drug screening, preclinical studies, cardiac contractility and signaling in hypertrophic cardiomyopathy and heart failure, with the overarching goal of uncovering new molecular mechanisms that serve as tractable therapeutic targets to improve heart health.
The lab utilizes multiple techniques to study basic molecular mechanisms of disease from molecules all the way through to the organism, including iPSC-derived cardiomyocytes, organoids, and animal models. This includes molecular biology (RNAseq and proteomics), biochemistry, measuring cardiac function (echocardiography), pressure volume loop (cardiac slicing), isolated cardiomyocytes (IonOpt,ix) and skinned papillary and myocytes (Aurora system), h-gh resolution confocal microsc,opy and in vivo studies.
Visa sponsorship is not available for this positions.
Outstanding U of A benefits include health, dental, and vision insurance plans; life insurance and disability programs; paid vacation, sick leave, and holidays; U of A/ASU/NAU tuition reduction for the employee and qualified family members; retirement plans; access to U of A recreation and cultural activities; and more! The University of Arizona has been recognized for our innovative work-life programs. For more information about working at the University of Arizona and relocations services, please click here.
Duties & Responsibilities- Lead research projects in close collaboration with the PI and other lab members.
- Innovate new areas of experimental inquiry.
- Advance technical aspects of experimental approaches and mechanistic understanding of biological problems.
- Mentor junior lab members and contribute to a productive scientific environment.
- Maintain detailed records and disseminate research findings in meetings and as manuscripts in scientific journals.
- Apply for independent funding and contribute to grant proposals submitted by the PI.
- There may be additional duties assigned as it relates to this position.
Knowledge, Skills, and Abilities:
- Ability to work efficiently, effectively and semi-independently on research projects within an area of specialization.
- Thorough technical and theoretical knowledge of research project and the objectives.
- Demonstrated aptitude to perform experimental protocols and procedures, including detailed data collection and analysis.
- Ability to communicate (grant and manuscript writing, oral presentation) effectively.
- Ability to present research finding on a regular basis to peers within the center and at national and international meetings.
- PhD in a related field, such as cardiovascular biology, with physiology, biochemistry, molecular and cellular biology.
- At least two first author publications.
- Experience in cardiac physiology, molecular and cellular assays, and rodent models of disease.
- 0-1 years postdoctoral experience preferred, although more experienced candidates with desired expertise will be considered.
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