About the role
<p><span style="text-decoration: underline;">Company Overview:</span></p> <p>Strand Therapeutics is a clinical stage biotechnology company utilizing synthetic biology to genetically program mRNA to deliver truly revolutionary immunotherapies to patients.</p> <p>Building on the idea of creating smart therapies based on Boolean logic circuits, Strand was started by biological engineers working together at MIT who were seeking to apply the concept of the emerging field of mRNA therapeutics. Strand's technology is therapeutic-area and mRNA modality agnostic where therapeutic proteins are encoded onto modified, self-replicating, or circular mRNA backbones which in turn are programmed with cell-specific sensors and circuits.</p> <p>Today, Strand has established three platforms with one clinical stage asset and several programs in preclinical development as well as early discovery. Our lead program, STX-001, is currently being evaluated in a phase 1 clinical trial for solid tumors. Our corporate headquarters is located in the Fenway district of Boston, Massachusetts.</p> <p><strong>Become the next standout single <em>strand!</em></strong></p> <p><span style="text-decoration: underline;">Job Summary:</span></p> <p>Strand is looking for people who have the enthusiasm and motivation to be a highly contributing member of a small but extremely productive team. This opportunity will offer the employee the ability to work in a matrix-based environment and be a part of the future strategy of the company.</p> <p>We are looking for a highly motivated and innovative candidate for the role of Scientist / Senior Scientist of Analytical Development. The expectation is that the Scientist / Senior Scientist will have experience independently executing analytical experiments using HPLC/UPLC techniques. Reporting to the Associate Director of Analytical Development, the right candidate will be a strategic thinker that brings a leadership presence and enthusiasm for Strand along with a desire to conquer new challenges.</p> <p><u>Primary Responsibilities:</u></p> <ul> <li>Leads development, execution, and validation of RP-IP/RP/IEX based analytical methods to establish identity, purity, potency, and stability criteria for early-stage mRNA and LNP formulations using UPLC-ESI-ToF, PDA, and CAD.</li> <li>Analyzes data and draws conclusions which drive screening, optimization, and scale-up efforts in mRNA and LNP Process Development.</li> <li>Serves as subject matter expert in analytical chemistry, mass spectrometry, and method qualification and transfer.</li> <li>Interfaces with external contract research organizations to ensure compliance with internal timeline and quality requirements.</li> <li>Mentors and develops junior scien