Executive Director, Pharmacovigilance

About Tenpoint Therapeutics

Tenpoint Therapeutics is a global, commercial-ready biotechnology company focused on developing groundbreaking treatments to rejuvenate vision in the aging eye. Its pipeline includes paradigm-shifting therapeutics for ophthalmic indications with significant unmet medical need, including presbyopia, cataracts, and geographic atrophy.

Our lead investigational asset, BRIMOCHOL™ PF, is designed to be the first and only combination therapy for presbyopia and has received a Prescription Drug User Fee Act (PDUFA) date of January 28, 2026. We are actively advancing preparations for a commercial launch in the first half of 2026.

We know our people are the driving force behind the success of our mission and vision. That’s why we offer a competitive benefit package to attract the very best talent to our team and to take care of our employees and their families.​​​​​​​ Below is a snapshot of our U.S. benefits package for full-time employees.

• Generous medical, dental, and vision health insurance plans
• Flexible spending accounts for health and dependent care
• Short-term, long-term, and life/AD&D insurance
• Employee Assistance Program
• 20 paid vacation days, 12 paid holidays, and 12 sick days
• 401(k) Retirement Plan with 100% company match up to 4% and immediate vesting
• Hybrid work options
• Wellness Resources
• Stock Options

For more information, visit www.tenpointherapeutics.com and follow us on LinkedIn, X, and Instagram.

Role Overview 

We’re seeking an Executive Director of Pharmacovigilance (PV) to establish, lead, and oversee all PV activities at Tenpoint. This individual will be the company’s sole internal PV expert and will partner closely with our third-party provider, to ensure compliant, effective pharmacovigilance systems and processes.

This is a rare opportunity to build PV capabilities in a growth-stage biotech on the cusp of commercialization, with direct impact on both patients and regulators’ confidence in our products.

Key Responsibilities 

• PV ownership: Serve as the single point of accountability for all pharmacovigilance activities across Tenpoint’s pipeline and commercial portfolio.
• Third-party management: Oversee and manage third party PV vendor as Tenpoint’s contract PV partner, ensuring quality, compliance, and alignment with business objectives.
• Procedure & process development: Establish and maintain internal PV policies, procedures, and processes that support regulatory compliance and organizational readiness.
• Regulatory compliance: Ensure adverse event reporting and pharmacovigilance operations meet FDA, EMA, ICH, and other applicable requirements.
• Cross-functional partnership: Collaborate with Clinical, Regulatory, Medical Affairs, and Commercial functions to integrate PV insights and support safe product development and commercialization.
• Safety leadership: Provide expert guidance on safety monitoring, signal detection, and risk management strategies.
• Executive engagement: Report PV activities, risks, and mitigation strategies directly to Tenpoint’s leadership team, ensuring proactive decision-making.

Experience 

Required: 

• 12+ years in pharmacovigilance or drug safety, with demonstrated leadership at the Director/Executive Director level.
• Proven track record of managing PV through a contract organization, including oversight of external partners.
• MD strongly preferred; other advanced life sciences degrees will be considered with significant PV leadership experience.
• Ophthalmology experience is strongly preferred; candidates with relevant specialty experience in adjacent therapeutic areas