Lab Manager / Senior Lab Manager

Wave Life Sciences is a biotechnology company focused on unlocking the broad potential of RNA medicines to transform human health. Our RNA medicines platform, PRISM, combines multiple modalities, chemistry innovation and deep insights in human genetics to deliver scientific breakthroughs that treat both rare and prevalent disorders. Our toolkit of RNA-targeting modalities including RNAi silencing and RNA editing provides us with unmatched capabilities for designing and sustainably delivering candidates that optimally address disease biology. Our diversified pipeline is focused on our obesity, alpha-1 antitrypsin deficiency and PNPLA3 I148M liver disease programs and also includes clinical programs for Duchenne muscular dystrophy and Huntington’s disease, as well as several preclinical programs utilizing our versatile RNA medicines platform. Driven by the calling to “Reimagine Possible”, we are leading the charge toward a world in which human potential is no longer hindered by the burden of disease.

Description

The Lab Manager will lead day-to-day laboratory operations for Discovery Biology and Chemistry teams in the Cambridge site, ensuring a safe, efficient, and compliant research environment. This role is responsible for equipment/instrument readiness, lab space and resource utilization, inventory and procurement, new hire onboarding, and sample/storage governance (including freezers and liquid nitrogen). The Lab Manager partners closely with scientists, Facilities, EH&S, IT, Supply chain/Logistics, and vendors to keep labs running smoothly and to support high-quality experimental execution.

Experience

• MS degree in science or technology, with 5+ years industrial experience; or BS degree in science or technology, with 8+ years industrial experience
• Hands-on lab experience with oversight/operations across biology and chemistry laboratory environments
• Demonstrated experience working with EH&S, Facility management, IT, Supply Chain or interface between internal stakeholders and external vendors
• Demonstrated excellent communication and interpersonal skills, with the ability to collaborate effectively across scientific teams, internal stakeholders and external partners
• Proven ability to organize and manage multiple priorities with strong attention to detail and follow-through

Responsibilities

• Laboratory Operations & Stakeholder Coordination
  • Coordinate with Facilities, EH&S, IT, Supply Chain/Logistics, external vendors, and scientific teams to ensure smooth laboratory operations and timely issue resolution, and serve as the primary operations point of contact for Discovery labs in the Cambridge site
• Equipment & Instrument Maintenance / Lifecycle Support
• Organize routine preventive maintenance (PM), calibrations (as applicable), and repairs for laboratory equipment and instruments
  • Partner with Facilities team throughout equipment lifecycle including new equipment request, support contract management, and end-of-life / replacement planning
• Lab Space, Shared Resources & Utilization
  • Act as the point person for maximizing utilization of shared lab equipment/instruments within existing lab space as well as support implementation of operational standards
• Inventory, Consumables, Procurement & Waste/Disposal
  • Own organization and management of lab supplies and consumables, in collaboration with Supply Chain 
  • Drive consistency in receiving, stocking, and storage practices to ensure uninterrupted lab operations
• Safety, Compliance, Training & Incident Reporting
  • Work with EH&S, Facilities, and scientific teams to coordinate: safety compliance activities as well as required training and onboarding documentation
• Cell Culture Room Hygiene & Scheduling
  • Specifically, maintain schedules and detailed task lists to ensure compliance with cell culture room hygiene requirements
• Sample & Cold Storage Governance (Freezers + Liquid Nitrogen)
  • Own and maintain inventory and optimal utilization of cold storage equipment, including SOPs for sample storage<