Senior Director, Global Clinical Data Management

Company Overview
ImmunityBio, Inc. (NASDAQ: IBRX) is a commercial-stage biotechnology company developing cell and immunotherapy products that are designed to help strengthen each patient’s natural immune system, potentially enabling it to outsmart the disease and eliminate cancerous or infected cells. We envision a day when we no longer fear cancer, but can conquer it, thanks to the biological wonder that is the human immune system. Our scientists are working to develop novel therapies that harness that inherent power by amplifying both branches of the immune system, attacking cancerous or infected cells today while building immunological memory for tomorrow. The goal: to reprogram the patient’s immune system and treat the host rather than just the disease.

Why ImmunityBio?
• ImmunityBio is developing cutting-edge technology with the goal to transform the lives of patients with cancer and develop next-generation therapies and vaccines that complement, harness and amplify the immune system to defeat cancers and infectious diseases.
• Opportunity to join a publicly traded biopharmaceutical company with headquarters in Southern California.
• Work with a collaborative team with the ability to work across different areas of the company.
• Ability to join a growing company with professional development opportunities.

Position Summary

The Senior Director, Global Clinical Data Management will provide strategic and operational leadership for all clinical trial data management activities across the global development portfolio. This role ensures delivery of high-quality, regulatory-compliant clinical datasets to support submissions, publications, and decision-making.   The Senior Director will define enterprise-wide clinical data governance strategy and ensuring consistent, high-quality data across clinical development, real-world evidence, and digital health programs.

Essential Functions

• Define and execute global Clinical Data Management (CDM) strategy across Phase I–IV clinical trials
• Lead end-to-end data management operations including CRF design, database build, edit check strategy, and database lock
• Responsible for the oversight of the Clinical Data Management team.  Lead and mentor the leadership team in the development and improvement of skills, knowledge and abilities to ensure strong succession planning and talent retention.
• Responsible for indirectly leading a team of Clinical Data Management Leaders in the planning, directing, and coordinating of all Clinical Data operations across the global segment.
• Own talent management processes at the leadership level.
• Ensure effective quality, efficiency, and timeliness of data management projects through appropriate resource allocation and work prioritization
• Establish global data standards, governance frameworks, and quality systems aligned with GCP, FDA, EMA, and ICH guidelines
• Oversee clinical data vendors (CROs, FSPs, external partners) ensuring delivery on time, within budget, and to quality standards
• Oversee data quality, lineage, traceability, and audit readiness systems
• Drive inspection readiness and regulatory audit support for clinical datasets
• Lead modernization initiatives including automation, AI-enabled data review, and advanced clinical data platforms
• Oversee Clinical Data Management budget planning, resource forecasting, and vendor contracts
• Build and manage a high-performing Clinical Data Management team through hiring, developing, and providing performance feedback to subordinate managerial and professional talent
• Collaborate within and across functional areas to evaluate, recommend, and implement process and technology improvement initiatives
• Ensure compliance with GCP, SOPs, and regulatory expectations
• Performs ad-hoc and cross-functional duties and/or projects assigned to support business needs and provide developmental opportunities.

Education & Experience

• Bachelor’s or Master’s degree in life sciences or technical discipline required
• 12+ years of clinical data, clinical operations, or healthcare data systems experience required
• Strong enterprise data governance experience required
• Experience developing and managing a team direct and indirect reports  required
• Experience managing a global team strongly preferred

Knowledge, Skills, & Abilities

• Deep knowledge of EDC systems, CDMS platforms, SDTM/CDISC standards
• Working knowledge of the clinical research, Good Clinical Practices, and regulatory requirements/guidelines
• Strong regulatory inspection experience (FDA/EMA)
• Str