Summer Intern/Sterile Drug Product Development

Why GSK?

Uniting science, technology and talent to get ahead of disease together.  

GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology). 

  

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.

Department Description

Drug Product Development-Steriles (DPD-Steriles), part of Medicine Development Supply (MDS), is a core R&D function that supports our Research Units in the design and development of new drug products encompassing both small and biopharmaceutical molecules. We bring together outstanding people across disciplines including formulation, packaging, biopharmaceutics, engineering, modelling, and process analytics to develop innovative, robust, and patient-centric medicines for sterile drug products from pre-clinical through the different phases of clinical development and commercialization. DPD-Steriles is accountable for the design, development and industrialization of drug products and their manufacturing processes.  This position is located at the Upper Providence site. 

Job Description

The Sterile Formulation Development Intern will be part of a team developing fundamental understanding of stabilization mechanisms for injectable formulations, with a particular emphasis on suspensions and/or solutions. 

 

Key learnings include: 

• Apply knowledge in colloidal science, leveraging expertise in pharmaceutical sciences, chemical engineering, and material science to understand the stabilization mechanism and therefore design robust suspension drug products. 

• Developing analytical methods to understand the molecular interaction and packing between various excipients and API, to understand the impact on critical quality parameters of drug products.​ 

• Determine important factors impacting the stability, manufacturability and performance of one or more of our sterile injectable drug delivery platforms such as solutions, micro and nano-suspensions. 

• Work closely with the material science team members to develop methods for material characterization. 

• Create a model and/or design space for a robust drug product by analyzing the data using statistical tools. ​ 

• Summarize key findings via periodic meetings, presentations, and draft reports. 

• At the end of the internship, you may have an opportunity to present the findings and conclusions to the department.  

• Comply with GMP requirements for recording experiments and data, and writing reports, including scientific review and data checking. 

• Comply with the requirements of Quality, Safety, and GSK policies and procedures to ensure that GSK intellectual property is protected. 

Minimum Qualifications

• Pursuing a Master's or PhD degree in Pharmaceutical Sciences, Chemical Engineering, Materials Science, Chemistry, or related disciplines. 
• Experience with DLS (dynamic light scattering), SEC (size exclusion chromatography), DSF (differential scanning fluorimetry), or DSC (differential scanning calorimetry).
• Knowledge of formulation science, material characterization and physical chemistry. 
• Must be able to work full-time (35-40 hours/week) throughout the12-week internship (May/June - August 2025).
• Must have an active student status and/or within 12 months post-graduation from an MS degree program. Post-doctoral candidates are not eligible.

Preferred Qualifications

• Automation experience and Statistical Analysis would be a plus.
• Basic understanding of injectable pharmaceutical formulations and manufacturing processes such as wet-bead media milling, homogenization, lyophilization etc. 
• Basic experience with techniques for studying molecular adsorption and adsorption modelling.