Principal Scientist, Process Technical Operations

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

This position offers an exceptional opportunity to provide strong technical leadership within a highly visible cross-functional team, driving the resolution of complex upstream and downstream manufacturing problems while ensuring the achievement of quality, schedule, and cost objectives. As a subject matter expert, the successful candidate will play a pivotal role in enabling effective collaborations with site and network support organizations (e.g. Manufacturing, Quality Assurance, Analytical, Technical Product Teams, and Manufacturing Sciences & Technology).  

Key Responsibilities: 

• Provide support to Upstream and Downstream Manufacturing for commercial biologic products manufactured in 24/7 operated manufacturing facilities: including stainless steel and single-use facilities.   

• Provides technical expertise for investigation and resolution of upstream process deviations, root cause investigation, CAPAs, process improvements and robustness, and review and approval of change controls.  

• Evaluates process performance by comparing manufacturing data to historical data through univariate and multivariate techniques with recommendations generated for process enhancement.  

• Routinely liaises with MS&T Process Champions, and Devens MS&T lab functions regarding strategies for technical and operational improvements, investigation resolution, and process validation.  

• Supports aspects of process technology transfer, process validation and the preparation of CMC documentation for regulatory filings and responses for the BMS Devens commercial manufacturing facility through cross-functional leadership and individual technical contribution.  

• Provides process subject matter expertise for regulatory inspections and other interactions with regulatory agencies, representing the Devens site.  

• Invests in the growth of the group, including current and future leadership, through assignment of development opportunities, coaching, mentoring, and administration of rewards and recognition.  

• Establishes high performance standards, defines clear accountability, and leads by developing, adopting, and supporting continuous improvement.  

• Actively communicates group’s activities and progress through varied technical and non-technical forums.  

Qualifications & Experience: 

• Knowledge of engineering and science attained through studies resulting in a BS (>8 years)/MS (>6 years)/PhD (>4 years) in Chemical or Biochemical Engineering, or its equivalent.  

• Expertise in upstream and downstream drug-substance bioprocessing is required.   

• Knowledge of at-scale mammalian-based biologics manufacturing processes is preferred.  

• Familiarity of