Lead/Staff Bioinformatician

POSITION SUMMARY:

Natera is currently seeking a Lead or Staff Bioinformatics Scientist to join our Oncology Bioinformatics team. The ideal candidate should have a strong background in data analysis for wet lab support and should have extensive experience with NGS data, with particular focus on building solutions for oncology applications. The individual will provide rapid prototyping and assembly of data from multiple sources and build tools to enable clinical interpretation. They will support the design, data analysis and interpretation of studies in the context of research, development, product validations, clinical trials, regulatory submissions, and scientific publications.

PRIMARY RESPONSIBILITIES:

• Collaborate with bench scientists to design and analyze experiments to evaluate novel assay technologies, and provide independent interpretation and recommendations for assay optimization.

• Build rapid prototypes and pipelines for custom analysis by integrating data from multiple Natera products.

• Develop algorithms and tools as necessary to support development of new products, including contributions to the bioinformatics pipeline.

• Act as an internal technical consultant to other functional groups or their members by providing expert advice on bioinformatics methodology.

• Work closely with interdisciplinary teams including assay, engineering, biostats, commercial and lab operations to support the development of new products.

QUALIFICATIONS:

• Master’s degree in bioinformatics with 10 years post-graduate experience, or PhD with 5 years of post-graduate experience (preferred)

KNOWLEDGE, SKILLS, AND ABILITIES:

• Expert knowledge of bioinformatics tools for NGS including all aspects of sequencing QC and secondary analyses including variant calling.

• Experience with WES/WGS/targeted sequencing of tissue and cfDNA as well as  somatic variant calling on these data.

• Strong programming and scripting experience in Python, R and shell.

• Fluent in all aspects of exploratory data analysis and visualization for complex data sets and ability to distill observations to actionable recommendations.

• Deep understanding of NGS workflows from sample extraction to sequencing.

• Familiarity with cloud computing and workflow management tools such as SnakeMake, WDL or NextFlow. 

• Ability to communicate effectively with wet lab groups and explain clearly technical bioinformatics concepts.

• Ability to work independently while managing multiple objectives and timelines

• Desire to work in a fast-paced environment with potential for high impact in a small team.

The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.Remote USA$146,900—$183,600 USD

OUR OPPORTUNITY

Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.

WHAT WE OFFER

Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!

For more information, visit www.natera.com.

Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives