Senior Manager, US Medical Affairs
Dyne TherapeuticsAbout the role
Company Overview:
Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. We are developing therapeutics that target muscle and the central nervous system (CNS) to address the root cause of disease. The company is advancing clinical programs for Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1) as well as a preclinical programs for facioscapulohumeral muscular dystrophy (FSHD) and Pompe disease. At Dyne, we are on a mission to deliver functional improvement for individuals, families and communities. Learn more at https://www.dyne-tx.com/, and follow us on X, LinkedIn and Facebook.
Role Summary:
Primary Responsibilities Include:
- Supports execution of US Medical Affairs tactical plans for the DMD program
- Assists in implementing scientific platform materials, congress planning, and medical education initiatives
- Contributes to cross-functional launch readiness activities to ensure alignment with program milestones
- Supports development and deployment of DMD-focused scientific materials, disease state education resources, and field medical tools
- Partners with the US MSL team to support KOL identification, engagement planning, insight gathering, and field metric tracking
- Translates field insights into actionable recommendations for Medical Affairs and cross-functional teams
- Tracks and monitors field activity and engagement effectiveness
- Contributes to development of scientific materials, field tools, and educational content
- Provides Medical review for promotional materials through the Promotional Review Committee (PRC)
- Maintains deep and current scientific knowledge in DMD and Dyne’s therapeutic platform
- Supports planning and execution of medical congresses, including onsite activities aligned to DMD milestones
- Coordinates logistics and execution of US advisory boards and expert engagements
- Partners with Patient Advocacy, Market Access, and Commercial teams to support aligned medical activities
- Ensures all activities comply with US regulatory, legal, and compliance standards
- Models Dyne’s core values through collaboration, accountability, and scientific integrity
Education and Skills Requirements:
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Advanced scientific or clinical degree required (PhD, PharmD, MD, or equivalent)
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7+ years of relevant Medical Affairs experience in pharmaceutical or biotechnology industry
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Rare disease experience preferred; neuromuscular disease experience a plusExperience supporting US-based medical tactics, congress activities, or field medical programs
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Strong scientific acumen with ability to translate clinical data for diverse audiences
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Excellent written and verbal communication skills
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Ability to operate effectively in a fast-paced, evolving environment with competing priorities
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Demonstrated ability to build collaborative relationships with internal and external
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to travel up to 25%, including occasional overnight and weekend travel
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Positive team orientation with strong alignment to Dy
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