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Upstream Process Development, Scientist / Senior Scientist

Zoetis
United Statesfull_timeVerifiedPosted 20 Mar 2026

About the role

Some roles ask you to follow a process. This one asks you to shape it. At Zoetis, we’re advancing the science of animal health—and we’re looking for a scientist or engineer who can run bioreactors, think in models, and turn data into decisions. At the junction of upstream bioprocess development and modern analytics, you’ll design studies with DoE, lead multivariate analysis, and build reproducible, interpretable models that drive process improvements and higher yields.

You’ll partner across biology, engineering, and data science by listening well, learning quickly, and communicating clearly to move decisions forward faster. If you’re ready to take ownership, change how we develop processes, and accelerate your career in a space where science meets purpose, we’d love to meet you.

Responsibilities

  • Design, run, and interpret mammalian cell culture experiments in shake flasks and bioreactors for monoclonal antibodies and proteins
  • Apply DoE, statistical models, and scale‑up principles to optimize processes
  • Lead multivariate analyses and modeling (e.g., PCA, time‑series analytics); develop and deploy reproducible analyses (notebooks/scripts) that inform decisions
  • Build pragmatic models (mechanistic or hybrid/ML where valuable) and validate with targeted experiments; document assumptions, limits, and outcomes
  • Leverage digital tools and data systems to improve process understanding and decision‑making; ensure data provenance and version control
  • Translate CFD modeling into actionable scaling and control strategies
  • Collaborate across upstream, downstream, formulation, and analytical teams to align priorities and move decisions forward
  • Document work in electronic lab notebooks and author high‑quality technical reports and decision memos
  • Support tech transfers and regulatory filings with clear, traceable documentation
  • Drive innovation by evaluating new bioprocess technologies and modeling approaches; create reusable templates and analysis pipelines to raise team velocity

Basic Qualifications

  • Bachelor’s degree in Biochemistry, Molecular Biology, Biotechnology, Chemical Engineering, Biological Engineering, Biomedical Engineering, or a related field, and 4+ years of relevant industry experience; or
  • Master’s degree in a relevant field and 1+ years of relevant industry experience; or
  • PhD in a relevant field with applicable research experience and/or industry experience.
  • DoE and multivariate analysis literacy; ability to design, run, and interpret statistically sound studies
  • Working knowledge of scientific computing/data analysis tools (e.g., Python, R, MATLAB, or equivalent) sufficient to run, adapt, and interpret analyses; capacity to ramp quickly
  • Experience producing reproducible analysis workflows (e.g., notebooks/scripts) and translating insights into experimental changes or control strategies

Preferred Qualifications

  • Strong upstream bioprocess foundation: cell culture and bioreactor operation (fed‑batch, perfusion)
  • Scale-up/scale-down fluency and mass transfer fundamentals
  • Exposure to mechanistic/kinetic modeling (e.g., Monod‑type kinetics) and practical ML; ability to connect model insights to biology
  • Familiarity with data systems and governance (ELN/LIMS, data provenance, version control) is a plus
  • Clear, first‑principles reasoning; can explain assumptions and design validation experiments
  • Success bridging bench science, process engineering, and data science; strong communication and organization

 

 

Full time

 

 

Regular

 

 

Colleague

 

 

Any unsolicited resumes sent to Zoetis from a third party, such as an Agency recruiter, including unsolicited resumes sent to a Zoetis mailing address, fax machine or email address, directly to Zoetis employees, or to Zoetis resume database will be considered Zoetis property. Zoetis will NOT pay a fee for any placement resulting from the receipt of an unsolicited resume.

Zoetis will consider any candidate for whom an Agency has submitted an unsolicited resume to have been referred by the Agency free of any charges or fees. This includes any Agency that is an approved/engaged vendor but does not have the appropriate approvals to be engaged on a search.

 

 

Notice: Zoetis Recruiters will contact candidates via email from an address ending in @zoetis.com and may also initially connect with candidates through LinkedIn, including LinkedIn InMail. Zoetis does not use Gmail, Outlook, Yahoo, or other web-based/generic email domains to communicate about job opportunities, interviews, or offers of employment. If you r

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