Senior Manager, Digital Strategy & Growth

About Us:

The Cancer Research Institute (CRI), established in 1953 and headquartered in New York City, is the preeminent U.S. nonprofit organization dedicated to saving more lives by fueling the discovery and development of powerful immunotherapies for all cancers. 

Guided by a world-renowned Scientific Advisory Council that includes four Nobel laureates and 35 members of the National Academy of Sciences, CRI has invested over $517 million in support of research conducted by immunologists and tumor immunologists at the world's leading medical centers and universities and has contributed to many of the key scientific advances that demonstrate the potential for immunotherapy to change the face of cancer treatment. The Cancer Research Institute's research funding supports the entire continuum of basic discovery through early-stage clinical development of novel cancer immunotherapies.

Role: The Senior Manager, Digital Strategy & Growth will lead the evolution of CRI’s digital ecosystem-  ensuring our website and marketing efforts effectively advance our mission, deepen engagement, and grow support for cancer immunotherapy research.

This role blends storytelling, technology, and data to create a digital experience that positions CRI’s website as a trusted destination for donor engagement, scientific authority, and patient education. At the same time, you will design and execute data-informed marketing strategies that expand CRI’s reach and strengthen our community of supporters.

We’re seeking a strategic and hands-on leader who can balance performance and purpose. The ideal candidate can optimize for growth while maintaining the integrity, credibility, and emotional resonance that define CRI’s brand. 

You will play a critical role in translating our impact into meaningful digital experiences, ensuring that every interaction- whether a website visit, social engagement, or donation- reflects our mission and builds long-term trust.

The ideal candidate thrives in a collaborative, fast-moving environment, brings a test-and-learn mindset, and is energized by using data, experimentation, and emerging technologies to drive measurable impact in our mission-driven organization.

This role is based in either New York City or Burlingame, CA with a hybrid schedule (at least 2 days/week in-office).

Responsibilities:

Website Strategy & Experience (≈50%)

• Own and lead CRI’s website strategy, aligning digital experience with organizational priorities, audience needs, and growth goals
• Partner with internal stakeholders (SciAffairs, Leadership, Comms) to translate CRI’s expertise into compelling digital thought leadership that reinforces CRI’s position as a leader in cancer immunotherapy
• Define and evolve website architecture, user journeys, and narrative hierarchy to support donor conversion, education, and engagement
• Establish and maintain content governance frameworks that prioritize SEO/AEO and discoverability, while ensuring consistency in voice, brand, and accessibility
• Lead conversion rate optimization (CRO) efforts through testing, personalization, and user experience improvements
• Collaborate with organizational leaders to prioritize and execute a scalable website roadmap
• Oversee CMS (WordPress) strategy, performance, and integrations

Performance Marketing & Digital Growth (≈50%)

• Develop and execute full-funnel performance marketing strategies across paid search, paid social, display, and emerging channels
• Set channel strategy, audience targeting approaches, and budget allocation to drive audience engagement, growth and acquisition 
• Optimize campaigns to drive measurable outcomes including traffic, lead generation, and donor acquisition
• Establish performance benchmarks and continuously refine strategies based on data, testing, and evolving organizational priorities
• Build and scale lifecycle marketing initiatives (retargeting, email integration, audience segmentation)

Data, Analytics & Systems

• Define KPIs and success metrics across website and performance marketing initiatives
• Build and maintain dashboards that provide clear visibility into performance (Hubspot, GA4, CRM)
• Partner closely with Salesforce/CRM leads to ensure seamless data flow and attribution

• Develop AI-native workflows to improve efficiency, automation, and