Embedded Caris Operations Manager - Charleston and Greenville, North Carolina

At Caris, we understand that cancer is an ugly word—a word no one wants to hear, but one that connects us all. That’s why we’re not just transforming cancer care—we’re changing lives.

We introduced precision medicine to the world and built an industry around the idea that every patient deserves answers as unique as their DNA. Backed by cutting-edge molecular science and AI, we ask ourselves every day: “What would I do if this patient were my mom?” That question drives everything we do.

But our mission doesn’t stop with cancer. We're pushing the frontiers of medicine and leading a revolution in healthcare—driven by innovation, compassion, and purpose.

Join us in our mission to improve the human condition across multiple diseases. If you're passionate about meaningful work and want to be part of something bigger than yourself, Caris is where your impact begins.

Position Summary
The Embedded Caris Operations Manager (ECOM) is an exempt, strategically focused professional responsible for optimizing end-to-end operational workflows supporting client precision medicine programs. This role serves as a trusted operational partner to providers, pathology teams, and internal stakeholders by ensuring reliable execution, workflow efficiency, and continuous process improvement across diagnostic testing and clinical coordination.
Operating with a high degree of autonomy and independent judgment, the ECOM owns workflow performance beyond transactional case handling, proactively resolving operational barriers and driving measurable improvements in quality, turnaround time, and client experience. This role is critical to enabling scalable, compliant, and high-impact precision oncology programs within embedded client environments.
The ECOM embeds directly within client sites to translate precision medicine strategy into consistent, executable operations. By reducing operational complexity, aligning stakeholders, and ensuring the right test is ordered, processed, and resulted at the appropriate point in the patient journey, the ECOM minimizes variation while maintaining compliance, auditability, and defensibility. Through proactive workflow ownership and continuous improvement, this role differentiates Caris through operational excellence and directly supports improved patient access to timely, high-quality molecular testing.

Key Responsibilities

• Own and manage the end-to-end lifecycle of assigned cases, ensuring accuracy, completeness, and timely progression from order submission through result delivery.
• Review, verify, and validate test orders, requisitions, and supporting documentation; proactively identify and resolve discrepancies or missing information.
• Coordinate with physicians, clinic staff, pathology teams, and internal departments to obtain clarifications and required documentation to maintain workflow continuity.
• Monitor case status, identify risks or potential delays, and implement corrective actions to protect turnaround time, quality, and case integrity.
• Serve as a subject matter expert on ordering requirements, workflow standards, and best practices for Caris testing.
• Submit required reports and documentation accurately and within established timelines.
• Develop and maintain working knowledge of Caris products, services, molecular profiling solutions, technology platforms, reimbursement processes, and billing workflows.
• Partner with physicians and clinical staff to support efficient order submission, adherence to testing requirements, and proper documentation.
• Provide guidance on clinical portals, EMR workflows, and documentation standards.
• Act as the primary point of contact for order-related questions and operational support.
• Reinforce best practices that improve documentation completeness, case quality, and turnaround time.
• Accurately document customer interactions, updates, and value-based activities in CRM systems.
• Support provider education initiatives aligned with workflow optimization and operational excellence.
• Coordinate operational logistics, including documentation management, report distribution, and internal handoffs.
• Triage billing inquiries and coordinate resolution with internal teams as appropriate.
• Maintain accurate tracking of case activity, workflow performance, and operational metrics.
• Execute responsi