Director, Global Site Engagement & Patient Recruitment

The Role: 

We are seeking an experienced Director, Global Site Engagement & Patient Recruitment, Respiratory Programs to lead site engagement and enrollment strategy across Generate’s late-phase global respiratory portfolio, including asthma and COPD studies. This is a people leader role responsible for building and executing a high-impact global model for investigator identification, investigator engagement, site performance, and patient recruitment across Phase II–IV clinical programs. 

This leader will manage and develop a team of Clinical Trial Liaisons (CTLs) and will partner closely with Clinical Operations, Clinical Development, Biometrics, and external CRO and vendor partners to identify investigators, accelerate enrollment, improve the site experience, and support high-quality trial execution. The Director will operate as both a strategic leader and a hands-on problem solver—using data, real-world insights, and strong site partnerships to identify high-performing sites and networks, remove enrollment barriers, and continuously strengthen study delivery across regions. 

Here's how you will contribute:

• Own and drive global site engagement and patient recruitment strategy across late-phase respiratory clinical programs, including Phase II, Phase III, and Phase IV studies in asthma and COPD. 

• Lead the development and execution of study- and program-level investigator identification, enrollment strategies that improve site readiness, recruitment performance, retention, and overall trial execution. 

• Manage, coach, and develop a team of CTLs, setting clear expectations, building capabilities, and creating a high-performance, collaborative, and accountable team culture. 

• Partner with Clinical Operations, Clinical Development, Biometrics, CRO and vendor partners to remove operational barriers, improve the site experience, and deliver studies on time. 

• Serve as a senior escalation point for site engagement and enrollment challenges, working directly with internal teams, CROs, investigators, and study sites to resolve issues quickly and effectively. 

• Use study performance data, site intelligence, and real-world insights to identify high-performing sites and networks and continuously refine site selection, activation, and enrollment strategies. 

• Shape global and regional site engagement plans that reflect country- and region-specific considerations, patient pathways, standards of care, operational realities, and representativeness goals. 

• Build and sustain strong relationships with investigators, site staff, site networks, and key external partners to strengthen Generate’s reputation as a thoughtful, responsive, and high-value sponsor. 

• Guide CTLs and study teams in the delivery of protocol and study-specific training to site personnel, ensuring consistent communication, protocol understanding, and operational readiness. 

• Oversee site-facing recruitment and retention approaches, ensuring messaging, materials, and support plans are practical, compliant, and tailored to the realities of respiratory trial execution. 

• Translate site feedback into actionable recommendations for protocol execution, recruitment planning, visit burden, and operational improvements. 

• Contribute strategically to protocol and study planning by bringing forward site, investigator, and patient insights that improve feasibility and reduce barriers to participation. 

• Monitor enrollment and site performance trends across the respiratory portfolio, proactively identifying risks, intervention opportunities, and lessons learned to inform future studies. 
• Maintain a working knowledge of global regulatory and GCP expectations related to trial conduct, site engagement, and enrollment execution. 

Leadership Responsibilities 

• Set a high bar for performance, accountability, and collaboration across the CTL team, with clear goals, timely feedback, and strong follow-through. 

• Build and develop a high-performing, diverse, and collaborative team by coaching individuals, sharing knowledge, and creating opportunities for growth.