Senior Scientist Discovery Immunology

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com

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Job Function:

Discovery & Pre-Clinical/Clinical Development

Job Sub Function:

Biological Research

Job Category:

Scientific/Technology

All Job Posting Locations:

San Diego, California, United States of America

Job Description:

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

About Immunology

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Our Immunology team leads in the development of transformational medicines for immunological disorders and illnesses. You can influence where medicine is going by restoring health to millions of people living with immune diseases. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

 

We are searching for the best talent for Senior Scientist to be in San Diego, CA

Position Overview:

We are seeking a Senior Scientist to join the Immunology Discovery group. The candidate will be lab-based, developing and executing experimental strategies to evaluate novel interventions in in vitro models of inflammation.

Key Responsibilities:

• Design, perform, and interpret in vitro experiments with a high degree of autonomy to support target validation, mechanism of action studies, and progression of drug discovery programs.
• Develop hypotheses with creative experimental designs to advance novel biology and targeting modalities
• Introduce state-of-the-art expertise in cellular assay technologies - assist with elevation of laboratory capabilities.
• Document research in internal discovery reports, manuscripts for external publication, and other formats as required.
• Work closely with colleagues from partner organizations to enable and/or support research activities.
• Present research at internal meetings and external scientific forums.
• Work with leadership to establish and maintain involvement in any external collaborations required to support research goals.

Requirements:

• PhD in Immunology/Pharmacology/Cell Biology or related discipline with 1-3 years additional lab experience
• Hands on experience with in vitro cellular models of inflammation required, including primary human immune cell isolation and cell culture, as well as experience with adherent, structural cell types (ex. fibroblasts, epithelium)
• Ability to independently design, execute, analyze, and accurately document laboratory experiments required
• Experience with standard methods for examination of gene and protein expression, including quantitative PCR, ELISA, MSD, western blot, and flow cytometry-based methods, are required
• Experience in profiling potency and mechanism of action of antibody and/or small