Jobs and Careers

Senior Director, Commercial Strategy

United States, United StatesRemotefull_timeVerifiedPosted 18 Aug 2026

💰 $275,000/yr($240,000/yr – $275,000/yr)

About the role

Company introduction:

Compass Pathways plc (Nasdaq: CMPS) is a biotechnology company dedicated to unlocking urgently needed new treatment options in mental health care.

The Company is headquartered in London, UK, with a U.S. office in New Jersey. We believe mental health patients deserve the possibility of a better future. Our initial focus is developing COMP360 psilocybin, a proprietary, investigational, synthetic psilocybin treatment under evaluation for treatment-resistant depression (TRD) and post-traumatic stress disorder (PTSD). COMP360 is a potentially first-in-class treatment and has Breakthrough Therapy designation from the U.S. Food and Drug Administration (FDA), as well as Innovative Licensing and Access Pathway (ILAP) designation in the UK for TRD.

We are leading the world’s largest classic psychedelic clinical program in TRD, and building upon that robust foundation, we are executing a late-stage trial evaluating COMP360 for PTSD, another condition with high unmet need. Our goal is to advance treatments that move the field of psychiatry towards treatment options that offer rapid onset and sustained durability with infrequent dosing. - Compass Pathways

Job overview:

The Senior Director, Commercial Strategy leads integrated launch planning for COMP360 in TRD, coordinating cross-functional activities across Commercial and key partner functions to ensure launch readiness. This role drives governance, execution, and visibility across milestones, risks, and dependencies to support a compliant and effective launch. This role is also future-focused, identifying opportunities for additional indications, studies, and growth for COMP360 and the organization.

Location: Hybrid in our Jersey City office or remote in the United States.

Reports to: Chief Commercial Officer.

Roles and responsibilities
(Include but are not limited to):

Act as a “Chief of Staff” for Commercial Strategy
Own the integrated launch plan for COMP360 in TRD, including critical path milestones, interdependencies, deliverables, assumptions, and key decision points
Lead cross-functional launch governance, establishing operating rhythms, meeting cadences, status reporting, and escalation pathways that support effective execution
Partner across Sales, Marketing, Market Access, Medical Affairs, Regulatory, Quality, IT, Finance, and Supply Chain to ensure launch activities are aligned, sequenced, and progressing against plan
Identify program risks, gaps, and bottlenecks early, and drive mitigation plans with appropriate owners to maintain readiness timelines
Build and maintain launch readiness frameworks, dashboards, and trackers that provide clear visibility to leadership on progress, risks, and resource needs
Coordinate the development of core launch enablers, including field readiness plans, systems readiness, process documentation, training coordination, and compliance-related activities
Support executive-level decision making by synthesizing complex cross-functional inputs into concise recommendations, trade-offs, and action plans
Ensure strong collaboration with commercial operations and technology partners to align systems, reporting, analytics, and tools required for launch execution
Manage external vendors and launch-related partners where applicable, ensuring timely delivery, clear accountability, and effective issue resolution
Contribute to post-launch planning, transition readiness, and lessons-learned processes to support sustainable execution beyond initial launch milestones
Strategy as it relates to additional indications, P3B/4 studies, RWE, etc.
Future focused planning for future indications including PTSD
Identify and explore other future opportunities for the company