Senior Data Scientist II

Who We Are & What We Do At Helix, our mission is simple: to help everyone improve their lives through their DNA.
Ready to make a real-world impact with your skills? At Helix, we're transforming healthcare by making genomics a standard of care. We partner with health systems and life science companies to accelerate the integration of genomic data into clinical practice. Join us in building a future where healthcare is personalized, proactive, and powered by genomics. 
As a Senior Data Scientist, you will:

• Analyze data to identify patterns and trends toward improving health and/or financial outcomes, e.g., disease prevalence, risk factors, treatment opportunities, and the effectiveness of health interventions
• Develop a portfolio of reports and data insights that communicates the value and opportunity of Helix population health, diagnostic, and research data for life science companies
• Develop reusable dashboards, analytical reports, datasets, and analytic integrations, by working with medical affairs, research, product, data science, and commercial teams where required
• Evaluate market opportunities by creating and maintaining therapeutic area and service line-specific data models
• Leverage real-world patient data spanning engagement, medical history, outcomes, social determinants, and genetics, partner with life sciences to provide focused and effective data-driven narratives
• Collaborate across multiple teams including analytics, data engineering, medical affairs, clinical, research, business development, strategy, and product

About you:

• Master’s Degree or higher in Data Science, Biostatistics, Medical Informatics, Epidemiology, Public Health, or other related scientific discipline
• At least 3 years of experience working with US healthcare data in health care plan/services, public health, RWE, research, or a related field
• Direct experience using LLMs or agentic tools (Claude Code, Cline, Copilot, etc) in a research or clinical data workflow
• Strong healthcare data experience with electronic health records and/or claims data
• Experience with common clinical coding standards (ex: ICD, CPT, LOINC, SNOMED-CT)
• Understanding of genetic data and knowledge of variant annotation tools and databases
• Strong programming skills in Data Analysis and Visualization, SQL, Python, Databases
• Strong analytical and problem-solving skills along with business acumen; desire to learn and grow in healthcare industry
• Worked with real world data and have a strong understanding of analytics and how it is leveraged within the life sciences industry
• Entrepreneurial spirit and willingness to jump into new areas
• Knowledge of population health metrics
• Excellent communication and storytelling skills with a variety of cross-functional stakeholders

 Pluses:

• Experience working with the OMOP CDM
• Experience working with large-scale genomic data
• Experience using Airflow, Nextflow, or other workflow orchestration
• Experience working in cloud environments
• Experience analyzing RWE data at or with life sciences customers

Expected Interview Process:1) Recruiter Screen 2) Manager Screen/Tech Screen 3) Onsite 4) Offer 
Expected Pay For This Role:There are 3 distinct parts to your Helix offer: 1) Base Salary 2) Annual Bonus 3) Equity 

• Expected Helix Base: $139,000 - $186,250
• Expected Helix Discretionary Annual Bonus: 10% of your annual salary
• Equity: We offer generous equity at Helix. If you receive a Helix offer your recruiter will book dedicated time with you to educate you on our equity model.

Aside from working alongside brilliant, dedicated, passionate, down-to-earth, curious, warm, and thoughtful people, we also provide great benefits:

• Comprehensive Health Insurance with Date of Hire eligibility 
  • Above average employer paid premium coverage 
• 12 weeks Helix Paid Parental Leave option 
• 401(k) with employer matching of up to 3% and 100% Vesting on the Date of Hire
• Comprehensive Well-Being Benefits 
• Flexible PTO
• Remote options for many roles and a home office stipend 

What To Expect During Your First 90 days:

• First 30 days: you’ll spend time learning the Helix way, completing training and onboarding for your roles, and getting introduced to your team and relevant stakeholders. You’ll