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Executive Medical Director, Global Medical Lead (Pain)

Vertex
United Statesfull_timeVerifiedPosted 15 Dec 2025
💰 $475,100/yr($316,800/yr$475,100/yr)

About the role

Job Description

General Summary:

The Executive Medical Director, Global Medical Lead (GML), Pain is a critical leadership role in Global Medical, responsible for the global medical strategy and implementation and tracking of global activities for a designated disease area(s). Key responsibilities include, but are not limited to, disease area specific Integrated Medical Plan development, including the publication plan, global launch strategy and execution, scientific leadership, external medical expert engagement, and strategic alignment with commercial and other cross-functional business partners. This leader will also be critical in leading post-approval evidence generation strategy in the disease area. This leader reports directly to the VP, Global Medical and is a core member of the Global Medical leadership team. They will lead the global medical affairs team for the designated disease area(s) and represents Medical Affairs in all Global strategic teams with Development and Commercial, including the Disease Strategy Team (DST) to drive cross-functional alignment, anticipate future needs, and contribute to Medical Affairs and Vertex’s long-term success. 

Key Duties and Responsibilities:

    Medical Strategy 

    • Lead the development, implementation, execution, and communication of the Integrated Medical Plans, including but not limited to medical strategy, global tactical plan, publication, congress and post-approval evidence generation plan, in collaboration with Clinical Development, HEOR, RWE, Medical Writing, and other internal stakeholders across Vertex  

    • Ensure alignment of medical strategy with organizational objectives by integrating individual and disease area team goals with Vertex and DST priorities, and the goals of cross-functional partners 

    • Expertly distills insights and actionable outcomes that inform strategy and drive the greatest impact for Medical Affairs  

    • Establishes and tracks medical KPIs that demonstrate impact on business and patient outcomes. 

    • Applies structured problem-solving and root cause analysis to identify solutions and make decisions that maximize medical and business impact 

    • Able to identify what is important and impactful to medical and the wider business, prioritize competing demands and communication to key stakeholders 

    • Account

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    Company

    Vertex

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