Associate Researcher I - Molecular & Cell Biology - Genetics & Genomic Sciences

The Associate Researcher I is a laboratory research position, responsible for independent conduct of routine and standardized experiments. This individual assists in the interpretation of research outcomes, performs assays to support research studies, and assists in the clerical and supply aspects of the laboratory environment.

We are seeking a highly motivated and detail-oriented Associate Researcher I to join our dynamic scientific team working to improve treatments for patients with rare metabolic diseases. In this role, you will provide critical laboratory support by executing core workflows in molecular biology, biochemistry, and mammalian cell culture. This is an excellent opportunity for an early-career scientist to build deep technical expertise, contribute to cutting-edge research projects, and work collaboratively in a structured, fast-paced laboratory environment.

1. Cell Culture & Maintenance (Approx. 40%)

• Maintain, passaged, and bank various mammalian cell lines using strict aseptic techniques.
• Monitor cell health, perform cell counting, and prepare cells for downstream experimental assays (e.g., transfections, drug treatments).
• Perform experimental assays with guidance of the PI.
• Prepare standard cell culture media, reagents, and buffers.

2. Molecular Biology & Biochemistry (Approx. 40%)

• Perform routine molecular biology techniques, including DNA/RNA extraction, PCR/qPCR, plasmid cloning, and gel electrophoresis.
• Execute biochemical assays such as Western blotting, ELISA, SDS-PAGE, Western blotting and protein quantification (BCA/Bradford assays).
• Assist in the preparation and characterization of biological samples.

3. Data Analysis & Documentation (Approx. 10%)

• Maintain a meticulous, up-to-date, and legally compliant Laboratory Notebook or Electronic Laboratory Notebook (ELN).
• Analyze experimental data using software tools (e.g., Excel, GraphPad Prism, ImageJ) and present clear summaries to supervisors.

4. Lab Operations & Safety (Approx. 10%)

• Ensure compliance with all laboratory safety guidelines, including hazardous waste disposal and biosafety level (BSL) protocols.
• Assist with general lab maintenance, including restocking supplies, tracking inventory, and calibrating standard lab equipment (pipettes, centrifuges, incubators).

• Bachelors or Masters degree in science or related field required (Molecular Biology, Biochemistry, Cell Biology preferred)
• No experience required. One=two years of related research experience preferred.

Preferred:

Technical Competencies

• Demonstrated hands-on experience with aseptic technique and mammalian cell culture.
• Familiarity with basic molecular biology methods (PCR, gel electrophoresis) and protein analysis (Western blotting).
• Experience with transient transfections, lentiviral production, or fluorescence microscopy is a plus.

Soft Skills

• Strong organizational skills with the ability to manage multiple tasks and timelines simultaneously.
• Excellent written and verbal communication skills for cross-functional collaboration.
• A high degree of reliability, attention to detail, and a strong problem-solving mindset.

 

 

Strength through Unity and Inclusion

The Mount Sinai Health System is committed to fostering an environment where everyone can contribute to excellence. We share a common dedication to delivering outstanding patient care. When you join us, you become part of Mount Sinai’s unparalleled legacy of achievement, education, and innovation as we work together to transform healthcare. We encourage all team members to actively participate in creating a culture that ensures fair access to opportunities, promotes inclusive practices, and supports the success of every individual.

At Mount Sinai, our leaders are committed to fostering a workplace where all employees feel valued, respected, and empowered to grow. We strive to create an environment where collaboration, fairness, and continuous learning drive positive change, improving the well-being of our staff, patients, and organization. Our leaders are expected to challenge outdated practices, promote a culture of respect, and work toward meaningful improvements that enhance patient care and workplace experiences. We are dedicated to build