Senior Scientist

Company Description

Insmed is a global biopharmaceutical company on a mission to transform the lives of patients living with serious and rare diseases. Our most valuable resource is our employees, and everything we do is motivated by a patients-first mentality. We are dedicated to growing our team with talented individuals from around the world who are willing to challenge the status quo, solve problems, and work collaboratively with a sense of urgency and compassion.

Guided by our core values of collaboration, accountability, passion, respect, and integrity, we aim to foster an inclusive, diverse, and flexible work environment, where our employees are recognized for leaning in and rolling up their sleeves. If you share our vision and want to work with the most dedicated people in the biopharma industry, come to Insmed to accelerate your career.

Recognitions

 

Consistently Ranked Science’s Top Employer

Insmed is dedicated to creating a collaborative environment where our team can thrive. Every day, our employees turn their passion for science and research into innovative solutions for patients. That’s why we’ve been named the No. 1 company to work for in the biopharma industry in Science’s Top Employers survey for four years in a row.

 

  

 

 

A Certified Great Place to Work®

We believe our company is truly special, and our employees agree. In July 2024, we became Great Place to Work-certified in the U.S. for the fourth year in a row. We are also honored to have been listed on the Best Workplaces in Biopharma™, Best Workplaces in New York™, PEOPLE® Companies That Care, Best Workplaces for Women™, Best Workplaces for Millennials™, and Best Medium Workplaces™ lists.

  

 

Overview

Insmed is seeking a Senior Scientist with significant experience with in vivo experiment management and execution. The scientist will be responsible for the execution of preclinical mouse models of neuro and muscular genetic diseases with research preparations of therapeutic constructs, including mouse genotyping, dosing, functional analysis, and tissue collection. Additionally, the scientist will document methods and studies and participate in the technical transfer of assays to third party contractors. Depending on experience, the scientist will work with current team members to develop new animal models. Beyond vivarium expertise, this position will also be responsible for histology techniques related to animal studies, including tissue collection, sectioning and staining. Familiarity with the use of a cryostat, histological techniques, and immunostaining techniques are required.

Responsibilities

• Handle mouse genetic models of disease, including breeding pairs, ID-tagging, injections (ICV and tail vein), and weighing.
• Tissue collection from mice on study and appropriate handling and storage of tissue.
• Use of cryostat to generate slides for histology.
• Execute staining protocols (eg. H&E) as well as immunohistochemistry.
• Documentation of results in appropriate formats provided by supervisor.

Position Requirements:

• Bachelor’s degree in Biology, or similar field of study, and 5+ years of industry experience.
• Histology proficiency required for sectioning and staining various in vivo samples for biodistribution.
• Experience analyzing functionality and survival data for ongoing experiments.
• Previous experience developing survival study graphs and survival curves.
• Experience organizing experiments and performing protocol writeups for developing R&D experiments.
• Knowledge of Good Documentation Practices and Good Laboratory Practices (GxP) is a plus.
• Proficiency in following protocols and working in a fast-paced, high-energy environment.
• Willingness to learn new techniques and train other laboratory staff in technical matters.
• Entrepreneurial spirit, with strong willingness to take on new challenges required to bring novel medicines to the clinic.
• Strict adherence to environmental, health, and safety guidelines.

Salary Range

$115,000 - $161,867 a year

Compensation & Benefits

We’re committed to investing in every team member’s total well-being, now and in the future. We offer a competitive total-rewards package to all employees around the world, including:

• Flexible approach to where and how we work, regionally based
• Competitive compensation package including bonus 
• Stock options and RSU awards
• Employee Stock Purchase Plan (ESPP)
• Flexible Vacation Policy
• Generous paid holiday schedule and winter break 

ADDITIONAL U.S. BENEFITS:

• 401(k) plan with company match
• Medical, dental, and vi