Executive Director, Technology Operations & IT Risk Management

Crinetics is a pharmaceutical company based in San Diego, California, developing much-needed therapies for people with endocrine diseases and endocrine-related tumors. We were founded by a dedicated team of scientists with the simple belief that better therapies developed from rigorous innovation can lead to better lives. Our work continues to make a real difference in the lives of patients. We have a prolific discovery engine and a robust preclinical and clinical development pipeline. We are driven by science with a patient-centric and team-oriented culture. Crinetics is known for its inclusive workplace culture. We are also a dog-friendly workplace. This is an exciting time to join Crinetics as we shape our organization into the world’s premier fully-integrated endocrine company from discovery to patients. Join our team as we transform the lives of others.

Position Summary:

The Executive Director, Technology IT Operations & IT Risk Management is a strategic and hands-on leader responsible for the comprehensive strategy, development, and operational management of Crinetics' global IT infrastructure, core enterprise platforms, IT operations, and information security program. This leader will manage all foundational technology, including cloud architecture, networks, and data centers, while also serving as the organization's leading advocate for Information Security.

This leader will be pivotal in driving operational excellence, maturing the company's security posture, and accelerating the pace of digital innovation to align with our fast-paced drug development and commercialization goals. This individual will lead a high-performing team, fostering a culture of accountability and continuous improvement. They will also serve as a key partner to the Enterprise Intelligence & Innovation team as well as the IT Business Partner team, building the scalable infrastructure required to advance the company's AI maturity and data strategies in a regulated GxP and SOX environment.

Essential Job Functions and Responsibilities: These may include but are not limited to:

Strategic Leadership & Technology Transformation

• Define and execute the multi-year strategy and technology roadmaps for Cyber Security, IT Infrastructure, IT Operations, and Platform Services, ensuring all functions scale effectively to support global expansion.
• Develop and manage the departmental budget, proactively improving the value-over-cost ratio and ensuring alignment with strategic plans.
• Collaborate and partner in the integration of emerging technologies to automate processes, enhance data utilization, and accelerate R&D, commercialization, and business operations.
• Lead, mentor, and develop a high-performing team of technology leaders and subject matter experts, fostering a culture of innovation and collaboration.

Cyber Security & IT Compliance

• Lead the development and implementation of a robust, risk-based cyber security program to protect critical assets, intellectual property, and internal/external sourced data.
• Establish and mature an integrated IT risk management framework and governance model to identify, assess, and mitigate technology-related risks effectively.
• Ensure strict adherence to relevant regulatory frameworks (e.g., GxP, SOX) and internal policies and manage responses to all IT audits.
• Manage security operations, including incident response, forensics, and remediation.
• Develop and implement a company-wide security awareness training program.

Core Technology Operations & Platforms

• Oversee the architecture, operations, and optimization of all enterprise IT infrastructure, including cloud environments (Azure preferred, AWS), networks, storage, and server systems, ensuring high availability, performance, and scalability.
• Direct the strategy and management of core Microsoft platforms and services (e.g., Microsoft 365, Azure Active Directory, Teams, SharePoint, Intune), maximizing their utility and security.
• Drive exceptional service delivery for all employees by maturing the IT Service Desk and End-User Computing (EUC) functions, focusing on modern tools, automation, and a user-centric service model.
• Provide seamless, high-quality IT operational support (Tier 1-3) to all users, including those in laboratory environments and remote field forces.

AI & DevOps Acceleration

• Through collaboration, champion and implement a DevOps and DevSecOps culture across IT, leveraging automation to enhance development lifecycles, streamline service delivery, and increase deployment velocity while ensuring continuous compliance and code integrity.
• Partner to identify, pilot, and contribute to the deployment of AI-driven solution