Executive Director, Global Commercialization Effectiveness

The Opportunity:

This is a rare and highly visible opportunity to help build something new at a pivotal moment in Revolution Medicines' growth. We are seeking an experienced and highly collaborative Executive Director, Global Commercialization Effectiveness to play a foundational role in establishing and scaling commercialization effectiveness as a core capability within the Global Commercialization organization.

This role sits within the newly formed Commercialization Effectiveness & Operations (CE&O) function and will be accountable for commercialization operations, project management, organizational effectiveness, and cross-functional integration across the commercialization organization.

You will partner closely with Global Commercial Leads, Global Medical Leads, Global Market Access Leads, regional leadership teams, and other cross-functional stakeholders to drive alignment, execution, and organizational effectiveness across a diverse portfolio of global commercialization priorities. You will define and continuously evolve the Global Commercialization operating model, ensuring effective integration across Commercial, Medical Affairs, Market Access, and regional organizations while enabling the company's long-term commercialization strategy. The role will establish scalable frameworks, planning processes, governance structures, and organizational capabilities that strengthen execution and support future growth.

Operating in a build-while-scaling environment, this leader will help shape how complex, cross-functional work gets done - bringing clarity, structure, and momentum while partnering closely with senior leaders across the organization. As the capability matures, this leader will build and lead a multidisciplinary organization spanning commercialization operations, project management, governance, planning, and organizational effectiveness.

What You’ll Do

• Serve as the primary integration leader across Global Commercial, Global Medical Affairs, Global Market Access, Regional Commercial Operations, and key corporate functions to ensure aligned planning, prioritization, and execution.

• Define and evolve the Global Commercialization operating model, establishing scalable frameworks that enable execution excellence and organizational effectiveness.

• Provide project management leadership and oversight for Global Commercialization Teams and Global Commercial Teams, ensuring alignment, accountability, and progress across strategic priorities through scalable project management capabilities and teams.

• Maintain overall accountability for execution across a portfolio of high-priority global commercial and commercialization initiatives, ensuring milestones, risks, dependencies, and decisions are effectively managed through appropriate governance, operating processes, and team leadership.

• Manage commercialization governance and planning processes, ensuring effective prioritization, resource allocation, decision-making, and escalation pathways across the commercialization organization.

• Build and scale commercialization effectiveness capabilities, including project management, operations, governance, planning, tools, dashboards, and performance management processes.

• Provide direct operational support to Global Commercial and Market Access organizations, ensuring efficient planning cycles, operational discipline, and execution consistency.

• Lead change adoption efforts related to new tools, processes, and ways of working, ensuring sustainable implementation across a global organization.

• Recruit, develop, and lead a high-performing team, creating scalable capabilities and ways of working that support the future needs of the organization.

Who You Are

You are energized by building infrastructure in ambiguous and rapidly evolving environments. You think in systems and excel at creating clarity, structure, and alignment across complex organizations. You bring a pragmatic, sol