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Executive Director, Strategy, Oncology R&D

AstraZeneca
Gaithersburg, United Statesfull_timeVerifiedPosted 11 Mar 2026
💰 $405,332/yr($270,222/yr$405,332/yr)

About the role

At AstraZeneca, every one of our employees makes a difference to patient lives every day. Each of us believes that science can change lives and to deliver this takes many people with many skill sets. When we deliver a life-changing medicine, that success comes from the combined efforts of all our people.

Oncology at AstraZeneca is unparalleled. We have created and strategically acquired one of the most promising Oncology pipelines in the industry.  You will be among inspiring oncology industry leaders who will keep you engaged and empower you to be the best. We seek out opportunities to do varied meaningful work which means we won't just follow the same course of action time and again if we can see potential in a different way of creating life changing medicine.

Our vision to tackle cancer is bold - we commit to pushing the boundaries of science to change the practice of medicine, transforming the lives of patients living with cancer, and ultimately eliminating cancer as a cause of death. No matter where our teams are based, we share a collective sense of urgency - to defeat cancer and improve the lives of cancer patients. At AstraZeneca, we have reinvented ourselves and developed a unique, differentiated strategy to fundamentally shift the way cancer is treated.

AstraZeneca has a strong and growing Oncology pipeline across multiple scientific pillars and tumor types. The continued success of this pipeline requires a team of highly skilled Strategy Leads to guide the creation of comprehensive therapeutic area strategies that integrate clinical, scientific, and commercial insights to shape portfolio decisions and break down complex investment decisions and priorities across assets and platforms.

As an Executive Director, Strategy, Oncology R&D, you will develop and deliver Therapeutic Area Strategy which may include a specific disease area and/or platform technology based on our latest priorities. This is a critical and exciting opportunity to use your scientific knowledge and strategic analysis expertise to lead and influence decisions that will have a direct impact on patients’ lives. Working at the highest level, you will ensure the decisions we make best position AstraZeneca for maximum return on investment and positive patient outcomes.  You will also be accountable for maintaining strong partnerships with the Senior Executive Team (SET) leaders and clear ways of working with our Competitive Intelligence, Business Development and Academic Partnerships team.

To be successful, you will need:

  • Clear and organized thinking with ability to simplify and prioritize complex problems

  • Strong understanding of financial evaluation of an asset or brand

  • Organizational awareness and experience of commercial pharmaceutical business planning

  • Ability to establish and maintain credibility with senior audiences

  • Familiarity with the oncology market and key trends with emerging science

This is an opportunity for a motivated, collaborative, data-driven leader to shape strategic direction and drive portfolio decisions that advance our bold ambition to one day eradicate cancer as a cause of death.

Accountabilities:

  • Develop and prioritize Oncology R&D portfolio strategy: Lead the creation of comprehensive therapeutic area strategies that integrate clinical, scientific, and commercial insights to shape portfolio decisions and investment priorities across assets and platforms.

  • Define strategic direction for growth: Establish and communicate clear strategic direction for near- and long-term growth, ensuring alignment with company-wide oncology objectives and addressing evolving market dynamics.

  • Advise executive senior leadership: Provide disciplined, insight driven recommendations on complex strategic topics to C-suite stakeholders, delivering clear and actionable guidance on portfolio optimization and investment decisions.

  • Partner across the enterprise: Collaborate with leaders across clinical development, discovery, business development, and other key functions to create cohesive long-term strategies that drive innovation and impact.

  • Analyze and generate strategic insights: Conduct rigorous analysis of internal and external data to identify trends, risks, and opportunities for portfolio growth and optimization, translating findings into actionable strategic recommendations.

  • Lead cross-functional collaboration: Foster a culture of collaboration, innovation, and accountability across all stakeholder groups, partnering with internal and external stakeholders to deliver on high-impact strategic objectives.

  • Drive effective communication: Ensure clear and compelling communication of

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Company

AstraZeneca

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