Principal Research Scientist II

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok.

Job Description

Purpose:

The Cell Culture Development organization within Operations leads the process development and tech transfer of cell culture processes for clinical manufacturing and commercialization of therapeutic proteins in the AbbVie pipeline. In addition, we provide subject matter expertise and experimental support for the manufacture of commercial biologics.

A successful candidate would be one of the senior leaders in the Cell Culture Development group and would be responsible for guiding a team of scientists and engineers in the definition and resolution of complex challenges presented by AbbVie’s robust, diverse biologics pipeline. The candidate would be expected to work together with cell culture scientists at AbbVie Bioresearch Center and other AbbVie sites to define and implement strategies for pre-clinical, early and late stage cell culture development and to identify and prioritize scientific and technological opportunities for investment that will result in robust, high-yielding processes.

Responsibilities:

• Leads a group of 5+ scientists and engineers with BS/MS and PhDs focused on bioprocess modeling, PAT and advanced bioreactor monitoring and control.
• Leads cell culture process development for monoclonal antibodies, bi-specifics, ADCs, fusion proteins and other molecular formats for early and late-stage clinical assets.
• Leads PPQ enabling cell culture process characterization activities.
• Leads/participates in cross-functional CMC teams and reviews relevant sections of regulatory submissions (e.g. IND, BLA, MAA, etc.).
• Advances technical expertise within the cell culture development field. Tracks emerging trends and technologies within the field through internal an