Senior Scientist, Protein Therapeutics

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference.
 

Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact.
 

We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together.

Job Description
 

Gilead's mission is to discover, develop, and deliver therapies that will improve the lives of patients with life-threatening illnesses worldwide.

Protein Therapeutics, the biologics discovery function within Gilead Research, is seeking an experienced and laboratory-facing senior scientist to join the Protein Science team to expand our research cell line engineering function. The successful candidate will apply state-of-the-art synthetic biology and cell engineering techniques to create research cell lines for recombinant protein production and support therapeutic candidate screening in vitro and in vivo across Gilead’s therapeutic areas including Virology, Oncology, and Inflammation. He/she will also develop membrane protein target-expressing cell lines to support Protein Therapeutics' antibody discovery and screening activities. In addition, he/she will implement new initiatives and technology development to achieve departmental goals.

Key Responsibilities

· Expand research cell line development function for target expression and therapeutic candidate production to support biologics discovery activities.

· Apply hands-on experience in cell engineering and implement new technologies to expedite the timeline from gene to protein expression.

· Employ functional genomics approach to enhance cellular processes in platform cell line to improve expression of target molecules.

· Support Protein Therapeutics to advance the biologics discovery campaigns from target identification to preclinical development.

· Provide scientific data to lead or support publications and patent filing efforts, and present in internal and external group meetings.

Basic Qualifications

Bachelors degree with 8 years of experience OR

Masters degree with 6 years of experience OR

PhD with 2 years of experience

Preferred Qualifications

· Ph.D. in Cell and Molecular Biology or related disciplines with postdoctoral training and 3+ years professional experience is strongly preferred. Master’s degree with at least 6 years or bachelor’s degree with at least 8 years of professional experience in a biopharmaceutical industry setting may also be considered.

· Proven track record and hands-on experience in cell line development and process developments for research purposes

· Experience in genetic engineering, CRISPR/Cas editing in mammalian cell line generation and characterization.

· Knowledge and skills in challenging membrane protein (e.g., multi-pass transmembrane proteins and surface protein complexes) expression in mammalian cells is highly desirable.

· Independent and critical thinking and scientific data management skills.

· Excellent oral and written communication skills.

· Demonstrated ability to work independently and effectively on multiple programs in a fast-paced and matrixed organization.

People Leader Accountabilities:

•Create Inclusion - knowing the business value of diverse teams, modeling inclusion, and embedding the value of diversity in the

way they manage their teams.

•Develop Talent - understand the skills, experience, aspirations and potential of their employees and coach them on current

performance and future potential. They ensure employees are receiving the feedback and insight needed to grow, develop and

realize their purpose.

•Empower Teams - connect the team to the organization by aligning goals, purpose, and organizational objectives, and holding

them to account. They provide the support needed to remove barriers and connect their team to the broader ecosystem.

 

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