Associate Director, Global Patient Safety, Systems & Analytics

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers.  The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity:

We are seeking an experienced and strategic safety systems leader to join our Global Patient Safety (GPS) department. The Associate Director, Systems & Analytics plays a critical leadership role in shaping, governing, and advancing the technology, data, and analytics capabilities that underpin RevMed’s global pharmacovigilance operations.

This role provides discipline‑level leadership across safety systems, data pipelines, analytics products, and operational governance. The Associate Director partners closely with Safety Operations, Safety Science, IT, Quality, and external vendors to ensure that GPS systems are scalable, compliant, inspection‑ready, and aligned with RevMed’s evolving portfolio and regulatory obligations.

The Associate Director leads cross‑functional initiatives, oversees system enhancements and integrations, and ensures that GPS has the technology and data foundation required to support high‑quality case processing, signal detection, and regulatory reporting.

The successful candidate will be a strategic, collaborative, and technically strong leader who brings deep expertise in pharmacovigilance systems and data. The candidate will meet the following requirements:

Management & Leadership Responsibilities

• Provide day‑to‑day leadership and direction to team members within Systems & Analytics, ensuring clarity of priorities, alignment to departmental goals, and consistent delivery of high‑quality work.

• through regular feedback, performance discussions, and growth‑oriented development plans.

• Set clear expectations for technical excellence, documentation quality, and operational rigor across all system and data activities.

• Foster a collaborative, inclusive, and high‑performance team culture, encouraging innovation, accountability, and continuous improvement.

• Oversee workload planning, resource allocation, and prioritization, ensuring the team can meet operational demands and strategic initiatives.

• Support recruitment, onboarding, and training of new team members to build a strong and scalable Systems & Analytics function.

• Provide leadership presence in cross‑functional forums, representing the Systems & Analytics discipline and ensuring alignment with Safety Operations, Safety Science, IT, and Quality.

• Ensure team members maintain inspection‑ready documentation, follow validated processes, and adhere to GxP and data‑integrity expectations.

• Guide staff through complex problem‑solving, helping them navigate ambiguity, assess risk, and make sound decisions.

• Model RevMed’s values and leadership behaviors, reinforcing a culture of quality, compliance, and operational excellence.

Systems Leadership & Governance

• Provide strategic direction for GPS systems, ensuring alignment with departmental and enterprise priorities.

• Lead the roadmap, governance, and lifecycle management of core safety platforms, including Safety One Argus, Safety One Intake, and analytics tools.

• Oversee system configuration, validation, and release management, ensuring compliance with global regulatory expectations.

• Partner with IT and Quality to maintain robust change‑control processes, audit‑ready documentation, and validated workflows.

• Anticipate system needs driven by portfolio growth, regulatory changes, and operational trends.

Data Quality, Analytics, & Reporting

• Oversee the design and maintenance of safety data outputs, ensuring accuracy, completeness, and traceability.

• Guide the development of analytics dashboards, operational metrics, and signal detection tools to support decision‑making across GPS.

• Establish data‑quality monitoring frameworks and lead cross‑functional efforts to resolve discrepancies and improve upstream data integrity.

• Ensure analytics outputs meet regulatory expectations for completeness, reproducibility, and inspection readiness.

Operational Excellence & Cross‑Functional Collaboration

• Serve as a primary tec