Senior Scientist - Nucleic Acid Delivery Biology

Career Category

Job Description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Senior Scientist

What you will do

Let’s do this. Let’s change the world. In this vital role you will join the Genetic Medicines team in Thousand Oaks, CA. As a new member of this team, you will be responsible for generating and implementing novel methods to deliver RNA-based therapies to previously unreachable cellular destinations across Amgen’s therapeutic areas.

• Help identify and implement new technologies to accelerate discovery at the leading edge of targeted delivery

• Generate and bring to life new approaches for realizing how extrahepatic RNA therapeutics can be deployed

• Collaborate closely with disease area, computational biology, and therapeutic development teams to make actionable decisions as a technical and intellectual subject matter expert

• Present research findings to cross-functional groups at internal and external meetings and publish scientific findings in peer-reviewed forums

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The professional we seek is an enthusiastic scientist with these qualifications.

Basic Qualifications:

• Doctorate degree PhD OR PharmD OR MD [and relevant post-doc where applicable]

Or

• Master’s degree and 3 years of relevant scientific experience

Or

• Bachelor’s degree and 5 years of relevant scientific experience

Preferred Qualifications:

• PhD or Master’s degree in Cell and Molecular Biology, Genomics, Genetics Biochemistry, or related disciplines with 2+years relevant industry or post-doc experience.

• Familiarity with oligonucleotide therapeutics or complex biologics

• Hands on experience with molecular and cellular biology techniques

• In vivo pharmacology or drug delivery model development experience

• Experience in design, execution, and optimization of experiments to evaluate intracellular perturbations and systemic responses to nucleic acid therapeutic delivery

• Experimental design of biodistribution, tissue and cellular level trafficking and functional delivery studies

• Independently plan experiments and collaborate with cross-functional partners to develop novel platform-specific structure activity studies

• Demonstrated track record of independent critical thinking, complex problem solving, and innovative research, evidenced by significant scientific contributions

• Excellent organizational and communication skills to give presentations in team meetings along with the ability to work in a flexible team-oriented environment

What you can expect from us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts

• A discretionary annual