Sr. Scientist, Biologics Design and Yeast Display, Discovery Biologics

Job Description

Senior Scientist, Biologics Design and Display, Discovery Biologics

We are on a quest for cures and are committed to be the world’s premier, most research-intensive biopharmaceutical company. Our teams combine leading drug discovery capabilities and world-class R&D with the purpose of turning breakthrough science into life-changing medicines.

We are seeking a Senior Scientist to join Biologics Design and Display team in the Boston Discovery Biologics group.  The successful candidate will be an integral member of the team responsible for developing and executing in vitro display campaigns to generate novel therapeutic hits and optimized leads. They will directly contribute to the discovery of novel biologics as well as platform build and technology optimization efforts. They will stay current with scientific progress and drive continuous innovation of display technologies to consistently deliver high quality early biologics to support drug discovery across multiple therapeutic areas. As part of project teams, they will collaborate across groups to solve complex problems in disease biology and drug discovery.  They will attend scientific conferences, contribute to publications, train and mentor junior stuff and interns, and help to set the group strategy. 

Responsibilities:

• Design and execute in vitro display campaigns for hit discovery and lead optimization to support the discovery and development of therapeutic candidates

• Leverage knowledge of NGS technology and computational sequence analysis tools to generate and evaluate multi-dimensional data from display campaigns in support of discovery and lead optimization workflows

• Stay abreast with external scientific and technological advancements and continuously drive innovation of display platform capabilities

• Collaborate across multiple functional areas to advance therapeutic candidates

• Effectively communicate experimental results in project and team meetings

• Promote external reputation of our Company’s Discovery Biologics

Qualifications & Experience

• PhD in Biology, Biochemistry, Chemistry, Engineering, Physics, Protein Sciences, Pharmaceutics, or a related life sciences STEM discipline with 0-3 years, MS with >3 years, or BS with >5 years of industry experience

• Experience in antibody discovery and optimization using in vitro display technologies

• Demonstrated strong analytical and problem-solving skills

• Excellent communication and organizational skills

Required skills:

• Deep hands-on expertise in at least one molecular display technology (phage, yeast, or mammalian)

• Familiarity with lead optimization strategies and display library design methodologies

• Hands of experience with NGS technology including NGS data generation and analysis

• Strong technical knowledge of molecular biology

• Effectively communicate experimental results in project and team meetings

Preferred skills:

• Hands on experience in both yeast and phage display

• Experience in using laboratory automation platforms for high through-put workflows

Your role at our company is integral to helping the world meet new breakthroughs that affect generations to come, and we’re counting on your skills and inventiveness to help make meaningful contributions to global medical advancement.

We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively for the common good. We are an equal opportunity employer, committed to fostering an inclusive and diverse workplace.

#EligibleforERP

Required Skills:

Accountability, Antibody Discovery, Biochemistry, Biological Sciences, Communication, Data Analysis, Detail-Oriented, Display Technologies, Flow Cytometry, High-Throughput Screening, Leadership, Microbiology, Molecular Biology Techniques, Next Generation Sequencing (NGS), Phage Display, Protein Analysis, Protein Engineering, Protein Interactions, Protein Purifications, Recombinant Protein Expression, Results-Oriented, Sanger Sequencing, Yeast Display

Preferred Skills:

Automation

Current Employees apply