Senior Clinical Genomics Scientist, R&D

POSITION SUMMARY: 

At Natera, our goal is to make personalized genomics and medicine a reality at scale. Clinical genomics focuses on the relationship between genes, and their variants, to clinical outcomes. As an R&D Clinical Genomics Scientist, you will be part of a small, focused team that is using science in order to build, support, and maintain a portfolio of germline and somatic genetic testing offerings, from panel concept to patient report. We shape Natera’s genomic tests via gene-disease curation, creating and automating scalable variant interpretation workflows, and providing expertise on a wide range of projects and products.

We are looking for a candidate who is passionate about the nuts and bolts of variant science, relentless about optimizing product quality, and most of all is excited about having their work used in the clinical care of millions of patients.

The Senior Clinical Genomics Scientist, R&D supports product development activities for variant curation and reporting process development. They are tasked with applying a variety of scientific principles and concepts to potential products and problems, and can work well in an exciting, fast-paced environment. This role will be heavily focused on inherited cancer and other common phenotypes. 

PRIMARY RESPONSIBILITIES: 

• Work primarily with Clinical Genomics R&D to support variant curation and reporting product development activities in a multidisciplinary team including laboratory directors, bioinformaticians, software engineers, and managers.
• Develop and maintain variant classification protocols with an emphasis on inherited cancer, common phenotypes, and diagnostic settings.
• Support new product development by applying variant- and gene-level expertise.
• Learn and understand the science behind ongoing research projects while simultaneously completing increasingly complex tasks as specified by the manager/director.
• Perform duties with minimal to moderate supervision; perform other tasks as specified by the manager/director.
• Develop plans, generate and advance new ideas; execute high complexity projects.
• Produce high-quality, reproducible results to a high technical standard.
• Maintain accurate and well-organized records, worksheets, and notebooks; summarize data in spreadsheets, graphs and presentations.

QUALIFICATIONS:

• Master’s degree in molecular biology, tissue or cellular biology, genetics, or closely related field; PhD or genetic counselor preferred. 
• Minimum of 3 years of clinical curation experience post-PhD or minimum of 5 years post-MS. 
• Product development experience is strongly preferred.
• Experience in a diagnostic clinical genomics setting strongly preferred; renal genetics and/or inherited cancer experience also strongly preferred.

KNOWLEDGE, SKILLS, AND ABILITIES:

Must Have:

• Expertise in genetic variant curation and/or interpretation of clinical relevance based on the AMP/ACMG guidelines.
• Familiarity with databases, tools, and resources commonly used in interpretation of genomic data.
• Excellent written communication skills to produce clear, concise and correct technical documentation.
• Ability and desire to communicate in cross-functional teams with members from varying backgrounds.
• Team player, self-motivated and detail-oriented.
• Duties may require working outside normal working hours (evenings and weekends) at times.
• This position can be home office based - 100% remote.

#LI-AE1 #LI-REMOTEThe pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.Remote USA$116,800—$145,950 USD

OUR OPPORTUNITY

Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease mana