Principal Scientist, Veterinary Pathology Board Certification
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Job Description
Our Company is a leading global biopharmaceutical company with over 125-year history of Inventing for Life with an inspiring mission to make discoveries that positively impact global healthcare. Our success is driven by putting patients first, operating with the highest integrity, and committing fully to our vision to make a difference in the lives of people globally. With our diverse pipeline of vaccines, biologics, small molecules, and newer modalities, we are at the forefront of research to advance the prevention and treatment of diseases such as cancer, cardiometabolic diseases, Alzheimer’s disease, eye diseases, and infectious diseases including HIV, Ebola and SARS-Cov2.
Our Company's Research Laboratories’ nonclinical safety assessment group at the West Point, Pennsylvania site is seeking an anatomic pathologist to join a highly collaborative team of scientists (14 anatomic pathologists, 3 clinical pathologists, and approximately 40 exceptional technical staff), working at a GLP-compliant facility with state-of-the-art anatomic, molecular and clinical pathology laboratories. Our team works on a diverse and exciting pipeline, participating in a wide variety of GLP-toxicology study types, many of which are run in-house, in addition to early discovery and investigative studies.
Pathologists at our company are integral members and leaders of collaborative cross functional scientific teams, addressing challenges from early discovery to late development. Our Company’s pathologists provide scientific leadership in the design and conduct of postmortem evaluation of studies and integrate the interpretation of postmortem data into the safety profile of drug candidates. Our Company's pathologists have diverse opportunities to learn and grow as professional scientists and drug developers through daily study related activities and collaborative works with diverse program development teams.
Key responsibilities for this scientific role include:
Employ routine H&E evaluations and specialized techniques to characterize the safety profile of new drugs from nonclinical toxicology and investigative studies
Work independently to create and interpret data, determine the significance of postmortem results, review literature
Opportunity to serve as Program Pathologist, providing scientific input and oversight across studies from very early discovery to late-stage development, following molecules throughout their development cycle
Communicate with study teams on postmortem findings and participate in projects to elucidate mechanisms of toxicity.
Provide scientific and technical guidance to technical staff.
Utilize tools and applications available on-site, including:
A robust historical control slide archive
Transmission electron microscopy
Immunohistochemistry and in situ hybridization
Qualitative and quantitative digital pathology
Our Company's pathologists have the opportunity to be mentored as nonclinical safety assessment leads on enterprise-level drug development teams:
Generating regulatory strategy
Overseeing the design and execution of nonclinical toxicology studies
Communicating with global regulatory agencies
Our Company's pathologists interact closely with each other, share slides and opinions, and help each other learn and grow
Required experience and skills:
Ability to collaborate with diverse cross-functional teams
An opportunity mindset
Doctor of Veterinary Medicine (DVM)
ACVP or ECVP-board certification in anatomic pathology
Preferred experience and skills:
Proficiency in evaluation and interpretation of toxicology studies
PhD in Toxicology, Pathology, or related discipline
Experience as a pathologist in biotech, pharma or CRO
Knowledge of drug discovery, development and regulatory processes,
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