Director, Global Health Economics & Outcomes Research (HEOR)

PTC Therapeutics is a global commercial biopharmaceutical company. For over 25 years our team has been deeply committed to a unified purpose: Extending life’s moments for children and adults living with a rare disease.

At PTC, we cultivate an inclusive culture where everyone feels valued, respected, and empowered. We welcome candidates from all backgrounds to join our team, fostering a strong sense of belonging.

Visit our website to learn more about our company and culture!
Site: www.ptcbio.com

Job Description Summary:

The Director of Global Health Economics & Outcomes Research Associate will participate in developing and implementing HEOR strategies that enhance the value proposition and supporting evidence of Sepiapterin, aiding its launch and post-launch phases. Additionally, the Director of HEOR is responsible for educating external customers about the clinical, economic, and humanistic impacts of PTC medicines and products to support formulary decision-making and improve population health.
The Director of Global HEOR also ensures compliance with relevant regulatory requirements and company Standard Operating Procedures (SOPs) as appropriate.

Job Description:

Responsibilities:

• Leads the execution of complex HEOR evidence generation strategies, including cost-effectiveness analysis, budget impact models, prospective and retrospective observational studies, ITCs, meta-analyses, systematic reviews, patient-reported outcomes measure development and validation, and other research necessary to support asset value.
• Collaborate with the In-House HEOR Team and Market Access Team to implement HEOR scientific engagement strategies for external customers, such as Payers, PBMs, GPOs, and Clinical Pathway companies, within a specific territory or customer base. Coordinate with other PTC colleagues as needed to ensure compliance and achieve HEOR goals.
• Serve as a conduit and resource for delivering scientific [clinical and healthcare economic information (HCEI)] to formulary decision-makers in accordance with PTC guidance.
• Proactively communicate clinical and economic information related to PTC disease or PTC product to support formulary decisions and enhance patient care outcomes.
• Respond to unsolicited customer requests for clinical and economic information related to PTC’s disease area or products to support formulary decisions and enhance patient outcomes.
• Capture and communicate customer insights with internal PTC's colleagues as appropriate, including identifying potential opportunities for research partnerships.
• Utilizes best practices to deliver essential input for designing PTC observational research studies.
• Collaborates with the medical communications teams on publication strategy and ensures that the dissemination of HEOR evidence is timely and maximizes impact.
• Collaborates internally with Medical, Clinical, Market Access, Regulatory, and Biostats to develop and implement HEOR strategies, supporting PTC product therapeutic value.
• Partners and works closely with Market Access to support the production of GVD and the Value Narrative.
• Perform other tasks and assignments as needed and specified by management.

Qualifications:

• Advanced degree (PhD, PharmD, MS) in health economics, public health, or a related scientific discipline, along with a minimum of 7 years of cumulative experience in health economics and outcomes research, within a pharmaceutical, biotechnology, or related environment.
• Strong track record of publication in peer-reviewed journals
• Strong technical expertise in HEOR and can formulate and lead innovative research projects, ensuring conduct is scientifically rigorous and aligns with best HEOR practices.
• Strong verbal and written communication skills, including presentation abilities to explain complex concepts and persuade others; comfortable adapting presentation style to various audiences.
• Ability to apply knowledge of global health technology appraisal requirements and clinical development to identify evidence gaps and formulate evidence generation strategies
• Demonstrate a breadth of diverse leadership experiences and capabilities, including the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues in a matrix environment to achieve meaningful outcomes and create business impact.
• Must possess a deep understanding of the current and future healthcare environment and a demonstrated ability to understand, interpret, and make recommendations concerning the evolving US healthcare marketplace.