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Senior Research Associate III - Vivarium Operations (24121-R-675-PCP)
ArsenalBioSouth San Francisco, United Statesfull_timeVerifiedPosted 30 Jul 2024
💰 $125,000/yr($102,000/yr – $125,000/yr)
About the role
WHO WE ARE:ArsenalBio, a privately held, clinical-stage programmable cell therapy company engineering advanced CAR T therapies for solid tumors, is seeking a talented Senior Research Associate III to work ONSITE based in our SOUTH SAN FRANCISCO office.
ArsenalBio’s mission is to develop efficacious and safe cellular therapies for patients with chronic diseases, initially cancer. With our programmable and computationally driven approach, our team is engineering living medicines to attack cancer’s inherent multi-faceted nature and overcome the challenges of addressing solid tumors with cell therapy.
Driven by a collective of diverse experts across immunology, synthetic biology, molecular biology, automation and computational biology, we are united in purpose to deliver radical breakthroughs for people with cancer, and prioritize the team’s outcomes over individual goals to achieve our company mission – together.
This means you’ll have the opportunity to work with the best talent in the field of cell therapy, and be part of ONE TEAM advancing therapies for patients who need it most.
We are seeking a highly motivated and experienced Senior Research Associate III to support vivarium and lab operations within the Pre-Clinical Pharmacology group at Arsenal Bio. Reporting to the Associate Director of Vivarium Operations, the successful candidate will work with teams to manage, maintain and acquire equipment and consumables necessary for organizational functionality.
In addition, the candidate will coordinate and execute daily tasks to support the In vivo Translational team as well as conduct key in vivo experimental activities. The candidate will communicate experimental data to support the progress of multiple internal and external collaboration research programs. This role requires an individual with outstanding self-initiative, attention to detail, experimental precision, analytical, and communication skills.
ArsenalBio has a generous and comprehensive benefits package that includes but is not limited to medical, dental, and vision as well as mental health resources, virtual and telehealth options, coaching, infertility treatment, parental leave and health savings accounts. We also offer flexible work schedules and flexible time off, which includes two extra “Arsenal Days o
ArsenalBio’s mission is to develop efficacious and safe cellular therapies for patients with chronic diseases, initially cancer. With our programmable and computationally driven approach, our team is engineering living medicines to attack cancer’s inherent multi-faceted nature and overcome the challenges of addressing solid tumors with cell therapy.
Driven by a collective of diverse experts across immunology, synthetic biology, molecular biology, automation and computational biology, we are united in purpose to deliver radical breakthroughs for people with cancer, and prioritize the team’s outcomes over individual goals to achieve our company mission – together.
This means you’ll have the opportunity to work with the best talent in the field of cell therapy, and be part of ONE TEAM advancing therapies for patients who need it most.
We are seeking a highly motivated and experienced Senior Research Associate III to support vivarium and lab operations within the Pre-Clinical Pharmacology group at Arsenal Bio. Reporting to the Associate Director of Vivarium Operations, the successful candidate will work with teams to manage, maintain and acquire equipment and consumables necessary for organizational functionality.
In addition, the candidate will coordinate and execute daily tasks to support the In vivo Translational team as well as conduct key in vivo experimental activities. The candidate will communicate experimental data to support the progress of multiple internal and external collaboration research programs. This role requires an individual with outstanding self-initiative, attention to detail, experimental precision, analytical, and communication skills.
WHAT YOU WILL DO:
- Support the Vivarium Operations and In Vivo Translation teams by conducting animal model studies in oncology to evaluate the activity of programmable cell therapy.
- Adhere to IACUC guidelines to ensure ethical treatment and welfare of laboratory animals.
- Maintain and expand cancer and therapeutic cell lines.
- Execute hands-on responsibilities including, but not limited to animal handling and restraint, administration via various routes, in-life measurements, clinical observations, sample collection and processing, and accurate data collection.
- Introduce and quantify tumor burden by volumetric measurement bioluminescent imaging.
- Harvest and analyze in vivo samples by flow cytometry and other in vitro assays.
- Document, organize, maintain, review, and report experimental records for research and regulatory requirements.
WHO YOU ARE:
- Masters in oncology, immunology, biotechnology or related field with 4+ years of relevant industry or academic experience or Bachelors degree with 6+ years relevant experience
- Cell culture experience with mammalian cell lines with additional weight given for CAR-T cells
- Animal health experience in identifying clinical observations and providing treatments
- Extensive experience in establishing mouse tumor models in immune competent and compromised animals
- Proficiency in drug administration (SQ, IP, IV, and PO)
- Proficiency in various blood collection routes (Sub-M and others)
- Proficiency in rodent full body necropsy
- Software experience in Excel, Google suite, Prism, Powerpoint, electronic lab notebooks, and in vivo data management platforms
- Ability to follow instructions and work independently
- Ability to effectively manage time and prioritize tasks to ensure all assignments are completed on or before deadlines
- Preferred experience with liquid handling equipment, flow cytometry, automation, and In Vivo Imaging System
- Must have excellent troubleshooting, organization, and planning skills, and the ability to work under timeline in a fast-paced environment
- Excellent written and oral communication skills
ArsenalBio has a generous and comprehensive benefits package that includes but is not limited to medical, dental, and vision as well as mental health resources, virtual and telehealth options, coaching, infertility treatment, parental leave and health savings accounts. We also offer flexible work schedules and flexible time off, which includes two extra “Arsenal Days o
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