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Medicinal Chemistry Research Scientist

Vertex
United Statesfull_timeVerifiedPosted 10 Dec 2025
💰 $150,000/yr($100,000/yr$150,000/yr)

About the role

Job Description

Vertex Pharmaceuticals has an exciting opportunity for a Research Scientist in the field of medicinal chemistry. Job responsibilities include the preparation of both single and focused sets of small organic molecules, developing and optimizing synthetic methods, creating and interpreting project-relevant Structure-Activity Relationship (SAR) and problem solving. Candidates must demonstrate an expert understanding of organic reaction mechanisms, formulation of executable synthetic routes, up to date understanding of contemporary synthetic methods as well as an ability to balance rational concepts with creativity which includes the development of new synthetic methodology as needed. The successful candidate will have the ability to work independently and be able to multi-task collaboratively in teams while adapting to rapidly changing needs. A strong desire to grow as a medicinal chemist while maintaining a passion for organic chemistry and the courage to challenge conventional wisdom are essential in this role.

Key Responsibilities

  • Maintain a high level of productivity in the laboratory setting
  • Develops and executes clear synthetic routes using state-of-the-art synthetic methodologies
  • Primarily responsible for executing organic syntheses in a timely, efficient, and independent manner
  • Create and interpret SAR with a clear understanding of the biological data
  • Organize and triage efforts to stay consistent with project priorities
  • Clearly and effectively communicate ideas and results (both verbally and in writing) to a broad range of audiences

Knowledge And Skills

  • Designs and executes complex, challenging chemistry experiments
  • Demonstrates astute understanding of his/her own discipline and the relevant literature
  • Maintains a high level of knowledge related to current developments in the scientific project field
  • Displays proven productivity and experimental creativity, and effective dissemination of ideas
  • Demonstrates effective, self-sufficient communication skills, especially in peer-directed presentations
  • Demonstrates awareness of other project-related disciplines and an understanding of general concepts and some experimental detail within those areas

 

Education And Experience
 

  • Ph.D. (or equivalent degree) in chemistry or related science 0-3 years of relevant post-doctoral employment experience, or
  • Master’s degree (or equivalent degree) in chemistry or related science and 3+ years of relevant employment experience, or
  • Bachelor’s degree (or equivalent degree) in chemistry or related science and 6+ years of relevant employment experience
  • Demonstrated effective communication skills, both verbal and written
  • Ability to navigate and be successful in a fast-paced, highly matrixed work environment
  • A desire to be part of a highly innovative company aimed at transforming the lives of people with serious diseases, their families and society

Pay Range:

$100,000 - $150,000

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.  From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

On-Site Designated

Flex Eligibility Status:

In this On-Site designated role, you will work

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Company

Vertex

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