Senior Scientific Director - Biotherapeutics & Cell Therapy

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

Sitting at the intersection of Research and Drug Development, Translational Medicine and Clinical Pharmacology is a passionate community of scientists, physicians, and related professionals dedicated to driving the science and portfolio decision-making to deliver the right drug, to the right patient, at the right dose, at the right time. We utilize the power of translational science and precision medicine to unlock the unique traits of individual patients and disease biology to inform practitioners about how to use BMS medicines to address unmet medical needs, and to identify new ways we can target disease to advance our portfolio. The Clinical Pharmacology and Quantitative Pharmacology & Data Analytics teams at BMS provide pharmacology and model-informed drug development support for all pipeline assets throughout the clinical development lifecycle. TMCP collaborates with departments across Development, Manufacturing, and Commercial to optimize dosing, formulation, delivery, and combination strategies, ensuring faster and more effective drug development informed by core scientific principals and data.

Position Summary

Bristol Myers Squibb (BMS) is a global biopharmaceutical company engaged primarily in the discovery, development and commercialization of novel therapies for the treatment of human diseases.

The Senior Scientific Director, Bioanalysis - Biotherapeutics & Cell Therapy will provide strategic and scientific leadership for bioanalytical activities supporting Biotherapeutics and Cell therapy assets across BMS’s nonclinical and clinical development programs as well as registrations.

As a functional leader within Precision Medicine, Bioanalytical and Translational Sciences (PMBATS), this role partners closely with Clinical Pharmacology, Translational Sciences, Nonclinical, Clinical Development, and Regulatory to enable critical program decisions and regulatory success. The position reports to the Executive Director, Bioanalysis, and leads internal teams and external partners globally.

Position Responsibilities

• Provide strategic leadership and accountability for bioanalytical PK and immunogenicity strategies across nonclinical and clinical development programs supporting biotherapeutics and cell therapies.

• Serve as the bioanalytical scientific lead on Project Teams, contributing to program strategy, risk assessment, and key decision making.

• Oversee the design, development, validation, and lifecycle management of bioanalytical assays, ensuring methods are fit‑for‑purpose and aligned with program and regulatory requirements.

• Partner cross‑functionally with internal Bioanalysis Lab Scientitsts, Clinical Pharmacology, DMPK, Nonclinical, Clinical, and Regulatory teams to deliver integrated PK, exposure, biomarker, and PD strategies.

• Drive innovation through the evaluation and implementation of emerging bioanalytical technologies, advancing operational efficiencies, and enabling risk‑based decision‑making approaches.

• Provide strategic oversight and hands‑on leadership for regulatory submissions (IND, NDA/BLA, IB, CTA, and related documents), including:

• - Authoring and reviewing bioanalytical and biomarker sections

• - Ensuring scientific rigor, consistency, and regulatory alignment

• - Leading responses to health authority questions for programs under direct responsibility

• Oversee external bioanalytical CRO partners, ensuring scientific quality, adherence to GLP/GCP requirements, and alignment with program timelines.

• Lead, mentor, and develop scientific ta