Senior Principal Scientist, Head of Checkpoint Immunology, Immunology Discovery

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok.

Job Description

The Immunology Discovery Department is seeking an accomplished and experienced Scientist to lead the Checkpoint Immunology Group within the Immune Tolerance Therapeutics Discovery team based in Cambridge MA. In this role you will lead a multidisciplinary team of highly talented scientists with experimental, technical and scientific expertise in ITIM-bearing inhibitory immune checkpoint receptors. The candidate should have a demonstratable track-record in this scientific discipline alongside a strong knowledge of preclinical drug discovery spanning target discovery / validation through to GLP tox phases. The ability to effectively collaborate and deliver results across multi-disciplinary line functions both internally and with external leading experts is required.  Proven expertise leading preclinical drug discovery programs targeting inhibitory receptors in autoimmune disease is an advantage. Applicants should have a strong publication record and have proven experience in leading (managing) & developing bench-based scientists.

Key Responsibilities:

• Lead the Checkpoint Immunology Group within Immunology Discovery. Responsible for refining the strategy and biology focus within this area to support and advance the portfolio
• Provide biology expertise to internal teams that helps pave the way for next-generation therapies that target inhibitory immune checkpoints in rheumatological, dermatological and gastroenterological diseases
• Key member of the Immune Tolerance Leadership Team, to support advancement of Immune Tolerance biology into the drug discovery pipeline
• Proven experience in managing, growing and developing highly talented scientists
• Drive performance by Lead