Jobs and Careers

Director Program Manager, Product Launch (Rare Disease)

Redwood City, United Statesfull_timeVerifiedPosted 9 Jul 2026

💰 $290,000/yr($240,000/yr – $290,000/yr)

About the role

Rezolute is a late-stage rare disease company focused on significantly improving outcomes for individuals with hypoglycemia caused by hyperinsulinism (HI). Our antibody therapy, RZ358 (ersodetug), is designed to treat all forms of HI and has shown substantial benefit in clinical trials and real-world use for the treatment of congenital hyperinsulinism (cHI) and tumor hyperinsulinism (tHI)

The Director Program Manager will be a key member of the Program Management Office (PMO), responsible for Launch execution plan for the company’s first rare disease drug launch. This individual will partner closely with key stakeholders and executives from Commercial, Medical Affairs, Regulatory, Manufacturing, Supply Chain to ensure operational readiness and alignment on critical path deliverables.

This role requires a proactive leader with exceptional organizational skills, strategic thinking, and the ability to influence without direct authority in a fast-paced, evolving environment.

Location: Redwood City California (in office role with travel as needed)

Key Responsibilities

Leads, facilitates, coordinates and guides all aspects of the Launch Plan, working closely with the Launch Team Leader (s) to enable a program to market.

Serve as the central point of coordination and communication to ensure the completeness and accuracy of the launch plan, its defined activities, timelines, and interdependencies.

The role will coordinate daily between the PMO and Commercial team Chief of Staff, maintaining and aligning the launch plan. The role will closely monitor tasks and deliverables, measuring variances, outlining risks and adjusting the plan to reflect change.

Supports cross-functional launch team meetings and ensure clear ownership, alignment, and accountability of tasks, milestones and deliverables in the Launch plan.

Develop and maintain dashboards, reports, and KPIs to track launch readiness and identify risks, gaps, and mitigations, supporting the consolidation and input into the enterprise PMO.

Support decision-making by ensuring timely escalation of critical issues and alignment with senior leadership.

Drive adherence to program governance, PMO best practices, and change control processes while working within the culture of the teams and company to obtain by in.

Build strong, trust-based relationships with functional leaders and project team members to drive collaboration and transparency.

Provide program management support to post-launch transition activities as needed.

Qualifications

Bachelor’s degree required; advanced degree (MBA, MS) preferred.
8+ years of experience in program or project management in the biopharmaceutical industry, with at least 3 years leading or supporting a commercial launch and/or pre-commercial readiness activity in rare disease.
Demonstrated familiarity / working knowledge of key commercialization functions in conduct of a rare disease product launch; Experience in rare disease, specialty products, or first-launch environments strongly preferred.
Demonstrated ability to manage complex, cross-functional projects and align diverse stakeholders.
Strong understanding of commercialization processes and timelines in the life sciences industry.
Excellent organizational, communication, and presentation skills.
Proficiency with project management tools (e.g., Smartsheet, MS Project) and collaboration platforms.
PMP or related certification a plus.

Key Competencies

Strategic and structured problem solver with strong critical thinking.
Highly collaborative and able to influence without authority.
Able to thrive in ambiguity and adapt quickly to changing priorities.
Results-driven with a sense of urgency and accountability.
Strong interpersonal and relationship-building skills.

Rezolute (RZLT) currently anticipates the base salary for the Director Program Manager role could range from $240,000 to $290,000 and will depend, in part, on the successful candidate’s geographical location and their qualifications for the role, including education and experience. This position will also be eligible for an annual performance bonus in accordance with the terms of the applicable plan (depending, in part, on company and individu