DPMS Manufacturing Execution Systems (MES) Engineer

Use Your Power for Purpose

Our breakthroughs would not make it to the hands of patients without our pharmaceutical manufacturing team. We rely on a team of dedicated and agile members who understand the importance and impact of their role in Pfizer’s mission. Patients need colleagues like you who take pride in their work and always look to improve outcomes. You will help to ensure that patients and physicians have the medicines they need when they need them. Your contributions will be vital in achieving project tasks and goals, fostering a collaborative team environment, and enabling Pfizer to reach new milestones and provide aid to patients worldwide.

What You Will Achieve

The DPMS Manufacturing Execution Systems Engineer I supports and advances key digital systems, process automation, data visibility, and data integration capabilities across Drug Product Manufacturing and Supply (DPMS). This includes support for manufacturing, materials planning, inventory management, and related DPMS processes.

This role provides critical engineering support within DPMS, helping ensure validated digital solutions, analytics, and core systems reliably enable daily operations, compliance requirements, and business growth initiatives.

Working in a structured environment, the MES Engineer applies foundational business analysis and digital skills through established procedures and documented practices. The role contributes to project tasks, system sustainment, and validated digital solutions that support compliant, reliable DPMS operations.

How You Will Achieve It

In this role, you will be responsible for:

Manufacturing Systems Support

• Support key digital systems within DPMS, including software and hardware applications used for manufacturing, materials management, and data capture and reporting.

• Systems include digital execution and orchestration systems (digital logbooks, Electronic Batch Records, Biosero), data capture systems (Aveva historians, networking and data flows, RFID, Snowflake) and physical automation systems.

• Daily support and troubleshooting of issues related to site manufacturing systems

• Ability to understand and adjust configuration settings and creation of new forms and workflows in the system.

• Support data strategy initiatives related to Manufacturing systems.

• Own and maintain configuration specifications and other technical documentation

• Incorporate new technologies, including Artificial Intelligence (AI) into the digital, manufacturing and materials management workflows.

• Support equipment integrations to Orchestrator (Biosero) in the Smartlab.

GMP Change Management & Validation Support

• Support GMP change management activities for DPMS digital systems, including documentation updates, testing support, and execution of approved changes.

• Assist in verification and validation tasks for software products and digital tools following established validation procedures.

• Maintain required system documentation and records in accordance with quality requirements.

• Assist with routine system maintenance activities, issue tracking, and coordination with IT partners, system owners, and vendors.

Digital Coordination & Engagement

• Support digital deployment and adoption activities across DPMS, including preparation of user materials, coordination of training logistics, and communication support.

• Serve as a supporting point of contact for DPMS digital initiatives, escalating questions and issues appropriately.

Qualifications

Must-Have

• Applicant must have a Bachelor’s degree in engineering, computer science, information systems or a related field with any years of experience

• Entry level to early career experience supporting digital systems, analytics, or business processes

• Basic understanding of computerized systems, data reporting, and business workflows.

• Strong attention to detail, documentation skills, and willingness to learn in a structured environment

• Ability to execute against Standard Operating Procedures and document entries in a compliant manner

• Demonstrated capability to work as a team member in a matrix development team• Strong analytical and computer skills

• Excellent oral and written communication skills

• Ability to maintain a safe work environment

Nice-to-Have

• Experience with one or more of the following platforms is a plus: Opstrakker, OSISoft PI/Aveeva historian, MS SQL, Python, Snowflake,