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Executive Director, Medical Affairs MSL (Nephrology)

Vertex
5010 - Vertex US - Distribution, United States, United Statesfull_timeVerifiedPosted 11 Dec 2025
💰 $408,000/yr($272,000/yr$408,000/yr)

About the role

Job Description

General Summary:

General Summary:

The Executive Director (ED), Medical Affairs MSL  focuses on the strategic direction of the field medical organization and the development of the leaders who will implement that strategyto ensure alignment of the assigned therapeutic/product and pipeline portfolio across diverse sets of external stakeholders. The Executive Director identifies, communicates, and addresses trends in the US healthcare environment and engages with cross-functional partners including research, clinical development, medical, and commercial teams in support of advancing the awareness and understanding of Vertex science.

The individual will build, lead and oversee a US Field Medical team >25 FTEs responsible for commercialization of our portfolio of medicines in a given therapeutic area. The leader of leaders manages a team of first-line managers (e.g. regional MSL Directors), with a focus on building a robust-high-performing field medical organization on a national scale. This includes making high-level decisions about budget, staffing, and resource allocation across the disease area.  The ED must maintain expertise across multiple mechanisms and treatment paradigms in a highly competitive marketplace and establish relationships with thought leaders (TLs). Additionally, this role is accountable for high-level strategy, business operations, and organizational direction as the portfolio moves towards commercialization. 

Key Duties and Responsibilities:

  • Develop and execute a comprehensive strategy for therapeutic area that aligns with Medical Strategy objectives and considers impact to enterprise business goals.
     
  • Lead, manage, coach and develop a large field team of 25+ individuals across the United States, holding them accountable to internal and external metrics measuring the impact of MSL interactions
  • Attract, hire, develop and retain top field medical talent; oversees team operational activities including personnel, financial resources, and training requirements.
  • Engage internal leaders across Vertex and external stakeholders to ensure that field medical is addressing the pressing needs of the healthcare community through continuous innovation while maintaining the highest compliance standards.
  • Ensure operational translation of corporate and medical strategic priorities into objectives, KPIs, and clear engagement guidance (e.g. MSL-clinical collaboration on studies, Thought Leader stratification and engagement planning, disease state education programs, evidence generation projects) based on region and country specific needs for the field medical organization.
  • Develop mutually collaborative partnerships with internal stakeholder groups such as US Medical Affairs Strategy Team, Global Medical, Med Comms, Medical Information and Medical Excellence, Clinical Development, RWE, HEOR and Commercial (Sales, Managed Markets).
  • Lead and direct Field Medical Operations to identify gaps and develop solution-oriented tools, technology infrastructure and training requirements necessary to fulfill field medical activities.
  • Partner effectively with the US MA Therapeutics Area Head to deliver the tools, resources and materials needed by the field teams to create meaningful scientific exchange.
  • Lead and encourage innovative approaches in field medical by staying abreast of industry benchmarks and evolving field models to maximize customer value and impact.
  • Implement strategies to build team capabilities in anticipation of and in response to the evolving internal and external environment. This includes leading external assessment initiatives that lead to a better understanding of the needs of external stakeholders.

Knowledge and Skills:

  • Proven track record of strong strategic leadership, teamwork, innovation, project management and demonstrated ability to manage, lead and mentor individuals
  • Demonstrated in-depth, specialized understanding of legal and regulatory guidelines of pharmaceutical industry
  • Performance oriented with business acumen and focus on customer service and patient-centric attitude
  • Excellent clinical and business acumen to drive improvements, innovation, and bottom-line results.
  • Exceptional communication and relationship building skills

Education and Experience:

  • Requires advanced degree in health sciences or related field, such as PharmD, PhD or MD degree
  • Requires 10+ years of experience in medical affairs with 5+ years focus on field medical capabilities, or equivalent combination of education and experience
  • Requires 5+ years of experience of le

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Company

Vertex

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