Sr. Director, Quality Management System (QMS) Team Lead

What You Will Achieve

The Senior Director, Quality Management System (QMS) Team Lead is a senior leader within QSEO Systems and Compliance (QSC) accountable for defining the global Quality Management System process strategy and governance in alignment with regulatory expectations and Pfizer standards. This role partners extensively with senior leaders and cross-functional business process owners to secure resources drive strategic execution and ensure effectiveness of Pfizer’s Quality System (PQS).

The Senior Director leads a team of senior quality professionals responsible for executing programmatic elements of the QMS framework and serving as the primary owner of system stability, performance monitoring and continuous improvement. They act as a team lead and mentor for Quality Operations colleagues, developing talent and enhancing organizational capability.

As the enterprise owner of the GMP/GDP QMS, the Senior Director provides strategic leadership of the GMDP Quality Manual, Level 1 Policies and Level 2 Procedures, ensures robust monitoring, proactive risk detection, and consistent governance. This role leads a GMP Quality Operational Committee or equivalent, ensures tiered review of key performance and risk indicators via Process Centric Teams (PCTs), and advances process optimization while leading cross-functional initiatives to strengthen quality systems and mitigating risk.

In addition, the Senior Director ensures appropriate escalation of emerging trends or risks to Executive Leadership (T5 and T6) through Management Notification, Quality Management Review or Quality Risk Review processes. They partner with senior leaders to align QMS priorities with business objectives, maintain a strong regulatory surveillance and intelligence program, influence external standards, and champions a culture of quality and compliance across a complex, matrixed organization.

The ideal candidate combines deep expertise in QMS leadership, multiple Operational platforms and strategy with the ability to deliver transformational improvements that sustain Pfizer’s commitment to quality and patient safety worldwide.

The Senior Director is accountable for governance across all tiers of the network, drives operational excellence, and prioritizes strategic initiatives that optimize performance across manufacturing and supply operations. This position influences senior leadership decisions, manages risk, and ensures implementation of robust processes that enable global quality and compliance.

In this role you will:

Strategic Leadership and Governance

• Define and drive execution of the global QMS governance strategy, ensuring compliance and continuous improvement across 50+ Level 2 processes.

•  Serve as the primary decision-maker for QMS governance policies, standards, and escalation management.

• Partner with senior leaders to align QMS priorities with business objectives and regulatory requirements.

• Ensure robust regulatory surveillance and intelligence are integrated into the QMS requirements, decision making, and risk detection.

• Collaborate with internal partners and external industry partners to benchmark, influence, and modernize best practices and maintain competitiveness in evolving regulatory environments.

• Facilitate timely data driven decision making within the business to support project schedules, budgets, and strategic commitments. 

• Define the global QMS end‑user enablement strategy; sponsor curricula and certification standards; ensure adoption and effectiveness through regional leaders and functional training owners.

• Design, lead and provide oversight for special assignments on various project teams and work streams

Enterprise QMS

• Design, lead and provide oversight for special assignments on various project teams and work streams

Continuous Improvement (CI) 

• Owner of the Continuous Improvement (CI) Loop for all QMS GMP/GDP processes across PGS and PharmSci

• Sponsor execution of high-impact CI initiatives to strengthen system performance, address systemic risks, and enhance operational effectiveness across PGS and PharmSci.

• Monitor and act on KPIs and governance dashboard for performance and identify systemic improvement opportunities.

• Oversee the QMS Project Management Office that governs across multiple tiers

Stakeholder Engagement & Influence

• Serve as a trusted strategic advisor